Objective Ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are chronic inflammatory
joint diseases, linking to the alterations of immune cells. We attempted to assess whether the …

The objective of the present study was to assess the prevalences of naive, memory,
memory/effector, regulatory and activated T-cells in peripheral blood (PB) and synovial fluid …

The aim of our study was to explore the relationship between circulating T cells and
ankylosing spondylitis (AS) and to find the role of the CD8+ CD122+ T cells in the …

Ankylosing spondylitis is a chronic inflammatory rheumatic disease, which is characterized
by inflammation of the spine and the sacroiliac joints. To date, the disease etiology remains …

Objective To determine the role of inflammatory mediators in the pathogenesis of ankylosing
spondylitis (AS), we investigated peripheral blood lymphocyte subsets and their intracellular …

Objective CD8+ T cells are abundant in rheumatoid arthritis (RA). However, their role in
disease pathogenesis is poorly defined. This study was undertaken to investigate the …

Little is known about the cellular characteristics of CD8+ T cells in rheumatoid arthritis (RA).
We addressed this by investigating whether the frequency of the CD8+ T cell subsets and …

Background Ankylosing spondylitis (AS) is a chronic inflammatory disease with worldwide
high prevalence. Although AS is strongly associated with HLA-B27 MHC-I antigen …

Objective Zygapophyseal joints of the spine are often affected in ankylosing spondylitis (AS).
In this study, we undertook a systematic immunohistologic evaluation of the …

Abstract Objective Th17 and Treg play important roles in AS, but their single and dual TCR
pairing types, ratios, and CDR3 characteristics remain unknown. Methods Single-cell RNA+ …