Autism is diagnosed by three major symptom categories: unusual reciprocal social
interactions, impaired communication, and repetitive behaviors with restricted interests …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social
communication deficits and other behavioral abnormalities. The three-chamber social …

Mouse models for the study of autistic-like behaviors are increasingly needed to test
hypotheses about the causes of autism, and to evaluate potential treatments. Both the …

Deficits in social interaction are important early markers for autism and related
neurodevelopmental disorders with strong genetic components. Standardized behavioral …

Social interactions are a fundamental and adaptive component of the biology of numerous
species. Social recognition is critical for the structure and stability of the networks and …

Main In recent years, substantial advances in social neuroscience have been realized,
including the generation of numerous rodent models of autism spectrum disorder. Still, it can …

Mouse models of social dysfunction, designed to investigate the complex genetics of social
behaviors, require an objective methodology for scoring social interactions relevant to …

A lack of automated, quantitative, and accurate assessment of social behaviors in
mammalian animal models has limited progress toward understanding mechanisms …

Autism is a pervasive developmental disorder, with characteristics including impairments in
reciprocal social interaction, impaired communication, and repetitive/stereotyped behaviors …

Behavioral therapies are currently the most effective interventions for treating the diagnostic
symptoms of autism. We employed a mouse model of autism to evaluate components of …