Activation of both adenosine A 2A and A 2B receptors (A 2B R) contributes to coronary
vasodilation. We previously demonstrated that uridine adenosine tetraphosphate (Up 4 A) is …

Uridine adenosine tetraphosphate (Up4A) has been identified as an endothelium-derived
contracting factor, which acts through purinergic P2X and P2Y receptors. Since the coronary …

Using various pharmacological methods, we previously demonstrated that the smooth
muscle and endothelium of porcine coronary artery contain vasorelaxant adenosine A2 …

To determine whether adenosine A3 receptors participate in adenosine-induced changes in
coronary flow, isolated hearts from wild-type (WT) and A3 receptor knockout (A3KO) mice …

To clarify which adenosine receptor subtype (s) are responsible for regulation of coronary
flow through endogenous adenosine, coronary vascular responses were examined in …

We previously demonstrated that uridine adenosine tetraphosphate (Up 4 A) exerts a potent
vasodilator effect in the healthy porcine coronary vasculature. Since the coronary …

To determine whether A1 adenosine receptors (AR) participate in adenosine-induced
changes of coronary flow, isolated hearts from A1AR−/− and A1AR+/+ mice were perfused …

Adenosine‐5′‐triphosphate (ATP) and adenosine are potent coronary vasodilators. ATP is
rapidly converted to adenosine by ectonucleotidases. We examined whether coronary …

Please cite this paper as: Berwick, Payne, Lynch, Dick, Sturek and Tune (2010). Contribution
of Adenosine A2A and A2B Receptors to Ischemic Coronary Dilation: Role of KV and KATP …

We tested whether hypoxia‐induced coronary artery dilatation could be mediated by an
increase in adenosine concentration within the coronary artery wall or by an increase in …