The element selenium (Se) was recognized only 40 years ago as being essential in the
nutrition of animals and humans. It is recognized as being an essential component of a …

Most epidemiological studies have shown inverse associations of selenium (Se) status and
cancer risk; almost all experimental animal studies have shown that supranutritional …

Although the average daily dietary selenium (Se) intake in the United States is consistently
above the adult RDA of 55μg Se/day, supranutritional supplements of 200μg Se/day have …

Methylated selenides are prominent metabolites at the dietary levels used for obtaining
anticarcinogenic effects with selenium. The present study reports the chemopreventive …

The nutritional functions of selenium (Se) are recognized as being due to a number of Se‐
containing proteins. It is not clear, however, whether any of these function in the anti …

The article reviews the progress in basic research of selenium and cancer prevention during
the past decade. Special emphasis is placed on the following four major areas of discussion …

Selenium is effective in reducing cancer incidence in animal models, and epidemiologic
data, as well as supplementation trials, have indicated that selenium is likely to be effective …

HERE IS INCREASING evidence in the literature that selenium supplementation can protect
labora-T tory animals against preneoplastic lesion development or tumorigenesis induced …

The anticarcinogenic activity of selenium in animal models is well established. The active
forms of selenium involved have not been identified to date, but conversion of selenium via …

Selenium was recognized as a nutritional essential only in the late 1950s. That it might also
be anticarcinogenic was first suggested a decade later based on ecological relationships of …