Background The relative effectiveness of second-generation (atypical) antipsychotic drugs
as compared with that of older agents has been incompletely addressed, though newer …

Background: In the treatment of schizophrenia, changing antipsychotics is common when
one treatment is suboptimally effective, but the relative effectiveness of drugs used in this …

Objective: The relative effectiveness of newly started antipsychotic drugs for individuals with
schizophrenia may depend on multiple factors, including each patient's previous treatment …

Background: The Intercontinental Schizophrenia Outpatient Health Outcomes (IC-SOHO)
study was designed to provide information regarding use and outcome of antipsychotic …

Objective: Whether there are differences in efficacy among second-generation
antipsychotics in the treatment of schizophrenia is a matter of heated debate. The authors …

Long-term outcomes for patients with schizophrenia have been disappointing. The article
discusses how the typical antipsychotics (clozapine and risperidone) as well as several …

BACKGROUND: Second-generation antipsychotics have largely replaced first-generation
antipsychotics for the treatment of schizophrenia, but a large-scale cost/effectiveness …

OBJECTIVES: To compare discontinuation rates of atypical antipsychotic agents in patients
with schizophrenia. METHOD: Adult Maryland Medicaid patients with schizophrenia were …

OBJECTIVE: The authors compared the efficacy and safety of three atypical antipsychotics
(clozapine, olanzapine, and risperidone) with one another and with haloperidol in the …

Background There is an ongoing debate over whether atypical antipsychotics are more
effective than typical antipsychotics in the treatment of schizophrenia. This naturalistic study …