Mechanisms of adiponectin action in fertility: an overview from gametogenesis to gestation in humans and animal models in normal and pathological conditions

A Barbe, A Bongrani, N Mellouk, A Estienne… - International journal of …, 2019 - mdpi.com
Adiponectin is the most abundant plasma adipokine. It mainly derives from white adipose
tissue and plays a key role in the control of energy metabolism thanks to its insulin …

Adiponectin and the control of female reproductive functions

MF Palin, VV Bordignon, BD Murphy - Vitamins & Hormones, 2012 - Elsevier
Adiponectin is the most abundant protein secreted by the white adipose tissue. It circulates
at high levels in the bloodstream and its serum concentration is inversely correlated with …

[HTML][HTML] The role of adiponectin in reproduction: from polycystic ovary syndrome to assisted reproduction

KG Michalakis, JH Segars - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To summarize the effects of the adipokine adiponectin on the reproductive
endocrine system, from the hypothalamic-pituitary axis to the gonads and target tissues of …

Adiponectin: a new regulator of female reproductive system

K Dobrzyn, N Smolinska, M Kiezun… - International journal …, 2018 - Wiley Online Library
Adiponectin is the hormone that belongs to the group of adipokines, chemical agents mainly
derived from the white adipose tissue. The hormone plays pleiotropic roles in the organism …

Adiponectin and adiponectin receptors in the mouse preimplantation embryo and uterus

ST Kim, K Marquard, S Stephens, E Louden… - Human …, 2011 - academic.oup.com
BACKGROUND Adiponectin (Adipoq), a protein secreted by adipocytes in inverse
proportion to the adipose mass present, modulates energy homeostasis and increases …

Adiponectin as a potential biomarker for pregnancy disorders

C Pheiffer, S Dias, B Jack, N Malaza… - International Journal of …, 2021 - mdpi.com
Adiponectin is an adipocyte-derived hormone that plays a critical role in energy
homeostasis, mainly attributed to its insulin-sensitizing properties. Accumulating studies …

Adiponectin and human pregnancy

S Mazaki-Tovi, H Kanety, E Sivan - Current diabetes reports, 2005 - Springer
Adiponectin is an adipose tissue-derived plasma protein that is involved in regulation of
insulin resistance and glucose hemostasis. Human pregnancy is characterized by an …

Adiponectin deficiency leads to female subfertility and ovarian dysfunctions in mice

L Cheng, H Shi, Y Jin, X Li, J Pan, Y Lai, Y Lin… - …, 2016 - academic.oup.com
Adipose tissue plays an important role in regulating female fertility, owing to not only its
energy stores but also the endocrine actions of secreted adipokines. As one of the …

Secretion of adiponectin by human placenta: differential modulation of adiponectin and its receptors by cytokines

J Chen, B Tan, E Karteris, S Zervou, J Digby… - Diabetologia, 2006 - Springer
Aims/hypothesis Pregnancy, a state of insulin resistance, is associated with elevated levels
of cytokines and profound alterations in metabolism. Serum adiponectin, an adipokine with …

The role of adiponectin in placentation and preeclampsia

EA Adu‐Gyamfi, LA Fondjo… - Cell Biochemistry …, 2020 - Wiley Online Library
Preeclampsia is not fully understood; and few biomarkers, therapeutic targets, and
therapeutic agents for its management have been identified. Original investigative findings …