The essential cellular process of ribosome biogenesis is at the nexus of various signalling
pathways that coordinate protein synthesis with cellular growth and proliferation. The fact …

Ribosomes play a pivotal role in the molecular life of every cell. Moreover, synthesis of
ribosomes is one of the most energetically demanding of all cellular processes. In eukaryotic …

Ribosome biogenesis is a fundamental process that provides cells with the molecular
factories for cellular protein production. Accordingly, its misregulation lies at the heart of …

Ribosome biogenesis is a highly regulated, essential cellular process. Although studies in
yeast have established some of the biological principles of ribosome biogenesis, many of …

The assembly of ribosomal subunits is a highly orchestrated process that involves a huge
cohort of accessory factors. Most eukaryotic ribosome biogenesis factors were first identified …

Ribosomes, which synthesize the proteins of a cell, comprise ribosomal RNA and ribosomal
proteins, which coassemble hierarchically during a process termed ribosome biogenesis …

Ribosome assembly is required for cell growth in all organisms. Classic in vitro work in
bacteria has led to a detailed understanding of the biophysical, thermodynamic, and …

Ribosome synthesis is a highly complex and coordinated process that occurs not only in the
nucleolus but also in the nucleoplasm and the cytoplasm of eukaryotic cells. Based on the …

Ribosomes are vital for cell growth and survival. Until recently, it was believed that mutations
in ribosomes or ribosome biogenesis factors would be lethal, due to the essential nature of …

Structure and Function of the Eukaryotic Ribosome: Cell Skip to Main Content Advertisement
Cell This journal offers authors two options (open access or subscription) to publish research …