No consensus view has been published on the relationship between the aldosterone
synthase gene (CYP11B2)− 344C/T polymorphism and left ventricular hypertrophy (LVH) in …

Background: Aldosterone synthase (CYP11B2) is one of the most studied candidate genes
related to essential hypertension (EH) and left ventricular hypertrophy (LVH). Some studies …

Aim: We performed a systematic review of the literature by means of a meta-analysis to
evaluate the influence of the aldosterone synthase gene (CYP11B2) C-344T polymorphism …

Objectives: The aim of our study was to evaluate the relationship between aldosterone
synthase gene polymorphism and cardiac dimensions in essential hypertension …

Objective To investigate the relationship of gene polymorphism of angiotension converting
enzyme (ACE), aldosterone synthase (CYP11B2) with essential hypertension (EH) and left …

Background—Aldosterone has direct and indirect effects on the heart, and genetic variations
in aldosterone synthesis could therefore influence cardiac structure and function. Such …

OBJECTIVES This study examined the association between the− 344 C/T polymorphism of
the human aldosterone synthase promoter and left ventricular structure in arterial …

Background Aldosterone has essential roles in regulating intravascular volume and blood
pressure, and is suggested to influence cardiac structure. However, the association of …

Background: Aldosterone plays an important role in development of left ventricular (LV)
hypertrophy and myocardial fibrosis. We assessed the influence of the T‐344C …

ABSTRACT Background and Objectives: Essential hypertension is a complex progressive
cardiovascular disorder. Renin–angiotensin aldosterone system (RAAS) plays a major role …