The Health for Life in Singapore (HELIOS) Study: delivering Precision Medicine research for Asian populations

X Wang, T Mina, N Sadhu, PR Jain, HK Ng, DY Low… - medRxiv, 2024 - medrxiv.org
Asian people are under-represented in population-based, clinical, and genomic research.,
To address this gap, we have initiated the HELIOS longitudinal cohort study, comprising …

Implementation of genomics in medical practice to deliver precision medicine for an Asian population

Y Bylstra, S Davila, WK Lim, R Wu, JX Teo… - NPJ Genomic …, 2019 - nature.com
Whilst the underlying principles of precision medicine are comparable across the globe,
genomic references, health practices, costs and discrimination policies differ in Asian …

Metabolic variation reflects dietary intake in a multi-ethnic Asian population

DY Low, T Mina, N Sadhu, K Wong, PR Jain, R Dalan… - medRxiv, 2023 - medrxiv.org
Dietary biomarkers reflecting habitual diet are explored largely in European and American
populations. However, the food metabolome is highly complex, with its composition varying …

Investigating How East Asian Medical and Biomedical systems Can Communicate: A Qualitative Exploration of How East Asian Medicine Concepts Can Be Used in …

JH Macbeth, L Conboy, M Engels, R Burack - medRxiv, 2024 - medrxiv.org
Title: A Qualitative exploration of how East Asian Medicine concepts can be used in modern
health research Purpose: There is much published science supporting East Asian Medicine …

Precision medicine and global health: the good, the bad, and the ugly

AFA Mentis, K Pantelidi, E Dardiotis… - Frontiers in …, 2018 - frontiersin.org
Precision medicine holds significant promise for finding new ways to diagnose, prevent, and
treat disease. In October 2017, Bill Gates and Francis Collins, thought-leaders in global …

Methylome-wide studies of six metabolic traits

HM Smith, HK Ng, JE Moodie, DA Gadd, DL McCartney… - medRxiv, 2024 - medrxiv.org
Exploring the molecular correlates of metabolic health measures may identify the shared
and unique biological processes and pathways that they track. Here, we performed …

Multifaceted genome-wide study identifies novel regulatory loci for body mass index in Indians

AK Giri, G Prasad, K Bandesh, V Parekatt, A Mahajan… - BioRxiv, 2019 - biorxiv.org
Obesity, a risk factor for various human diseases originates through complex interactions
between genes and prevailing environment that varies across populations. Indians exhibit a …

Time for real-world health data to become routine

A Abernethy - Nature Medicine, 2023 - nature.com
Time for real-world health data to become routine | Nature Medicine Skip to main content
Thank you for visiting nature.com. You are using a browser version with limited support for …

Harnessing technology and molecular analysis to understand the development of cardiovascular diseases in Asia: a prospective cohort study (SingHEART)

J Yap, WK Lim, A Sahlén, CWL Chin… - BMC Cardiovascular …, 2019 - Springer
Background Cardiovascular disease (CVD) imposes much mortality and morbidity
worldwide. The use of “deep learning”, advancements in genomics, metabolomics …

Protocol for a prospective, observational, deep phenotyping study on adipose epigenetic and lipidomic determinants of metabolic homoeostasis in South Asian …

N Nadiger, S Devi, T Thomas, A Sivadas… - BMJ open, 2021 - bmjopen.bmj.com
Introduction We describe the rationale and broad study design of the Indian Diabetes and
Metabolic Health (InDiMeT) study, a new prospective, observational study incorporating …