Post-transcriptional dynamics and RNA homeostasis in autophagy and cancer

SP Kolapalli, TM Nielsen, LB Frankel - Cell Death & Differentiation, 2023 - nature.com
Autophagy is an essential recycling and quality control pathway which preserves cellular
and organismal homeostasis. As a catabolic process, autophagy degrades damaged and …

The autophagy–RNA interplay: degradation and beyond

MH Abildgaard, SH Brynjólfsdóttir, LB Frankel - Trends in Biochemical …, 2020 - cell.com
Autophagy is a highly conserved degradation pathway that ensures nutrient recycling and
removal of unwanted substrates. This process has a fundamental role in stress adaptation …

[HTML][HTML] The role of non-coding RNAs in autophagy during carcinogenesis

P de la Cruz-Ojeda, R Flores-Campos… - Frontiers in cell and …, 2022 - frontiersin.org
Macroautophagy (autophagy herein) is a cellular stress response and a survival pathway
involved in self-renewal and quality control processes to maintain cellular homeostasis. The …

Emerging connections between RNA and autophagy

LB Frankel, M Lubas, AH Lund - Autophagy, 2017 - Taylor & Francis
Macroautophagy/autophagy is a key catabolic process, essential for maintaining cellular
homeostasis and survival through the removal and recycling of unwanted cellular material …

The new kids on the block: RNA‐binding proteins regulate autophagy in disease

S Dushnitzky, H Ishtayeh, A Ashkenazi - The FEBS Journal, 2024 - Wiley Online Library
Mammalian autophagy is a highly regulated and conserved cellular homeostatic process. Its
existence allows the degradation of self‐components to mediate cell survival in different …

[HTML][HTML] Transcriptional and post-transcriptional regulation of autophagy

Q Ma, S Long, Z Gan, G Tettamanti, K Li, L Tian - Cells, 2022 - mdpi.com
Autophagy is a widely conserved process in eukaryotes that is involved in a series of
physiological and pathological events, including development, immunity, neurodegenerative …

The role of epigenetics and non-coding RNAs in autophagy: A new perspective for thorough understanding

S Talebian, H Daghagh, B Yousefi, Y Ȍzkul… - Mechanisms of ageing …, 2020 - Elsevier
Autophagy is a major self-degradative intracellular process required for the maintenance of
homeostasis and promotion of survival in response to starvation. It plays critical roles in a …

On the edge of degradation: autophagy regulation by RNA decay

E Delorme‐Axford, DJ Klionsky - Wiley Interdisciplinary …, 2019 - Wiley Online Library
Cells must dynamically adapt to altered environmental conditions, particularly during times
of stress, to ensure their ability to function effectively and survive. The macroautophagy …

[HTML][HTML] Oncophagy: harnessing regulation of autophagy in cancer therapy

JS Gundara, JT Zhao, BG Robinson… - Endocrine-related …, 2012 - erc.bioscientifica.com
Autophagy is an increasingly well-characterised process of cell component auto-digestion
and recycling thought necessary for cellular subsistence. As we gain a more thorough …

The update on transcriptional regulation of autophagy in normal and pathologic cells: A novel therapeutic target

Z Zhang, M Guo, S Zhao, W Xu, J Shao, F Zhang… - Biomedicine & …, 2015 - Elsevier
Autophagy is a genetically programmed, evolutionarily conserved catabolic process that
occurs in response to stress. While short-lived proteins are degraded via the …