Despite endorsed and exponential research to improve diagnostic and therapeutic
strategies, efforts have not yet converted into a better prospect for patients infected with the …

Abstract Coronavirus disease 2019 (COVID-19) is a new infectious disease that currently
lacks standardized and established laboratory markers to evaluate its severity. In COVID-19 …

Platelets, as nonnucleated blood components, are classically recognized for their pivotal
role in hemostasis. In recent years, however, accumulating evidence points to a …

For the past 150 years, platelets have been recognized as the major blood component that
mediates hemostasis and thrombosis. In more recent years, however, we have come to …

Thrombocytopenia, characterized by a decrease in platelet count, is commonly observed in
sepsis and COVID-19. In sepsis, thrombocytopenia can result from various mechanisms …

Introduction: Multiple lines of evidence have attested that decreased numbers of platelets
may serve as a surrogate marker for poor prognosis in a wide range of infectious diseases …

Although platelets are traditionally recognized for their central role in hemostasis, the
presence of chemotactic factors, chemokines, adhesion molecules, and costimulatory …

Roles of platelets during infections surpass the classical thrombus function and are now
known to modulate innate immune cells. Leukocyte-platelet aggregations and activation …

Rationale: In addition to the overwhelming lung inflammation that prevails in coronavirus
disease 2019 (COVID-19), hypercoagulation and thrombosis contribute to the lethality of …

In 2019 first reports about a new human coronavirus emerged, which causes common cold
symptoms as well as acute respiratory distress syndrome. The virus was identified as severe …