[HTML][HTML] Apoptosis induced by Staphylococcus aureus toxins

X Zhang, X Hu, X Rao - Microbiological research, 2017 - Elsevier
Apoptosis stimulated by bacterial toxins is common during infection and is now considered
important in disease processes. As a major human pathogen, Staphylococcus aureus also …

α-Toxin is a mediator of Staphylococcus aureus–induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signaling

H Bantel, B Sinha, W Domschke, G Peters… - The Journal of cell …, 2001 - rupress.org
Infections with Staphylococcus aureus, a common inducer of septic and toxic shock, often
result in tissue damage and death of various cell types. Although S. aureus was suggested …

Staphylococcus aureus α-toxin-induced cell death: predominant necrosis despite apoptotic caspase activation

F Essmann, H Bantel, G Totzke, IH Engels… - Cell Death & …, 2003 - nature.com
Recent data suggest that α-toxin, the major hemolysin of Staphylococcus aureus, induces
cell death via the classical apoptotic pathway. Here we demonstrate, however, that although …

Exploring the Role of Staphylococcus aureus in Inflammatory Diseases

H Chen, J Zhang, Y He, Z Lv, Z Liang, J Chen, P Li… - Toxins, 2022 - mdpi.com
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

Staphylococcus aureusα‐toxin induces apoptosis in peripheral blood mononuclear cells: role of endogenous tumour necrosis factor‐α and the mitochondrial death …

B Haslinger, K Strangfeld, G Peters… - Cellular …, 2003 - Wiley Online Library
Staphylococcus aureus infections can result in septic and toxic shock with depletion of
immune cells and massive cytokine production. Recently, we showed that, in S. aureus …

Staphylococcus aureus Toxins: An Update on Their Pathogenic Properties and Potential Treatments

N Ahmad-Mansour, P Loubet, C Pouget… - Toxins, 2021 - mdpi.com
Staphylococcus aureus is a clinically important pathogen that causes a wide range of
human infections, from minor skin infections to severe tissue infection and sepsis. S. aureus …

Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

D Oliveira, A Borges, M Simões - Toxins, 2018 - mdpi.com
Staphylococcus aureus is a microorganism resident in the skin and nasal membranes with a
dreadful pathogenic potential to cause a variety of community and hospital-acquired …

Multiple virulence factors are required for Staphylococcus aureus‐induced apoptosis in endothelial cells

B Haslinger‐Löffler, BC Kahl, M Grundmeier… - Cellular …, 2005 - Wiley Online Library
Staphylococcus aureus infections can result in sepsis and septic shock associated with
vascular damage and multiple organ failure. Apoptosis appears to play a key role during …

Involvement of α5β1‐integrin and TNF‐α in Staphylococcus aureus α‐toxin‐induced death of epithelial cells

X Liang, Y Ji - Cellular microbiology, 2007 - Wiley Online Library
Staphylococcus aureus causes suppurative infections which are often associated with tissue
destruction and cell death. In the present study, we investigated the molecular and cellular …

Staphylococcus aureus α-toxin induces apoptosis in endothelial cells

BE Menzies, I Kourteva - FEMS Immunology & Medical …, 2000 - academic.oup.com
The internalization of Staphylococcus aureus by cultured human umbilical vein endothelial
cells was recently shown to induce apoptosis. We examined the role of α-Toxin, a major …