Updates in PTSD animal models characterization

L Zhang, XZ Hu, H Li, X Li, T Yu, J Dohl… - … Disorders: Methods and …, 2019 - Springer
Post-traumatic stress disorder (PTSD) is a chronic, debilitating mental disorder afflicting
more than 7% of the US population and 12% of military service members. Since the …

Animal models for the discovery of novel drugs for post-traumatic stress disorder

PR Zoladz - Expert Opinion on Drug Discovery, 2021 - Taylor & Francis
Introduction Existing pharmacological treatments for PTSD are limited and have been used
primarily because of their effectiveness in other psychiatric conditions. To generate novel …

Modeling trauma to develop treatments for posttraumatic stress.

EG Lowery-Gionta, MD May, RM Taylor… - Translational Issues …, 2019 - psycnet.apa.org
Posttraumatic stress disorder (PTSD) is a chronic mental health disorder that impairs daily
functioning and reduces overall quality of life. Current treatments are effective only in some …

Animal models of post-traumatic stress disorder and recent neurobiological insights

AM Whitaker, NW Gilpin, S Edwards - Behavioural pharmacology, 2014 - journals.lww.com
Post-traumatic stress disorder (PTSD) is a complex psychiatric disorder characterized by the
intrusive re-experiencing of past trauma, avoidant behavior, enhanced fear, and …

Current status of animal models of posttraumatic stress disorder: behavioral and biological phenotypes, and future challenges in improving translation

J Deslauriers, M Toth, A Der-Avakian, VB Risbrough - Biological psychiatry, 2018 - Elsevier
Increasing predictability of animal models of posttraumatic stress disorder (PTSD) has
required active collaboration between clinical and preclinical scientists. Modeling PTSD is …

[HTML][HTML] Current status of animal models of PTSD: behavioral and biological phenotypes, and future challenges in improving translation

J Deslauriers, M Toth, A Der-Avakian… - Biological …, 2018 - ncbi.nlm.nih.gov
Increasing predictability of animal models of posttraumatic stress disorder (PTSD) has
required active collaboration between clinical and preclinical scientists. Modeling PTSD is …

Animal models in translational studies of PTSD

NP Daskalakis, R Yehuda, DM Diamond - Psychoneuroendocrinology, 2013 - Elsevier
Understanding the neurobiological mechanisms of post-traumatic stress disorder (PTSD) is
of vital importance for developing biomarkers and more effective pharmacotherapy for this …

Toward animal models of post-traumatic stress disorder

H Cohen, G Richter-Levin - Post-Traumatic Stress Disorder: Basic Science …, 2009 - Springer
Although animal models for PTSD are limited to the assessment of measurable and
observable behavioral parameters and cannot assess complex psychological symptoms …

Genome to phenome: a systems biology approach to PTSD using an animal model

N Chakraborty, J Meyerhoff, M Jett… - … : Methods and Protocols, 2017 - Springer
Post-traumatic stress disorder (PTSD) is a debilitating illness that imposes significant
emotional and financial burdens on military families. The understanding of PTSD etiology …

Post‐traumatic stress disorder and beyond: an overview of rodent stress models

J Schöner, A Heinz, M Endres, K Gertz… - Journal of cellular …, 2017 - Wiley Online Library
Post‐traumatic stress disorder (PTSD) is a psychiatric disorder of high prevalence and major
socioeconomic impact. Patients suffering from PTSD typically present intrusion and …