Novel insights into the emerging role of Neat1 and its effects downstream in the regulation of inflammation

Y Pan, T Wang, Z Zhao, W Wei, X Yang… - Journal of …, 2022 - Taylor & Francis
Nuclear paraspeckle assembly transcript 1 (Neat1) located at chromosome 11 is a long non-
coding RNA that is widely expressed in mammalian cell types, and which is overexpressed …

Long non-coding RNA NEAT1-centric gene regulation

Z Wang, K Li, W Huang - Cellular and Molecular Life Sciences, 2020 - Springer
Nuclear paraspeckle assembly transcript 1 (NEAT1) is a long non-coding RNA that is widely
expressed in a variety of mammalian cell types. An increasing number of studies have …

Long non-coding RNA nuclear paraspeckle assembly transcript 1 promotes activation of T helper 2 cells via inhibiting STAT6 ubiquitination

S Huang, D Dong, Y Zhang, Z Chen, J Geng, Y Zhao - Human cell, 2021 - Springer
Abstract T helper (Th) 2 cell-medicated immune response participates in various immune
diseases, including systemic lupus erythematosus (SLE). Long non-coding RNA nuclear …

[HTML][HTML] The role of long noncoding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) in immune diseases

D Jing, F Zhu, Z Xu, G Zhang, G Zhou - Transplant Immunology, 2022 - Elsevier
The long noncoding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) has
been shown to be involved in the pathogenesis of several diseases. Herein, we discuss …

NEAT1 accelerates the progression of liver fibrosis via regulation of microRNA-122 and Kruppel-like factor 6

F Yu, Z Jiang, B Chen, P Dong, J Zheng - Journal of Molecular Medicine, 2017 - Springer
Long non-coding RNAs (lncRNAs) have been reported to be involved in many important
biological processes including proliferation, apoptosis, differentiation, and survival …

Long non-coding RNA NEAT1 knockdown alleviates rheumatoid arthritis by reducing IL-18 through p300/CBP repression

T Guo, Y Xing, Z Chen, H Zhu, L Yang, Y Xiao, J Xu - Inflammation, 2022 - Springer
Rheumatoid arthritis (RA) is chronic inflammatory autoimmune disease. The crucial role of
long non-coding RNA (lncRNA) in the progression of RA has been highlighted. Hence, this …

Cellular, physiological and pathological aspects of the long non-coding RNA NEAT1

PK Lo, B Wolfson, Q Zhou - Frontiers in biology, 2016 - Springer
BACKGROUND The majority of mammalian genomes have been found to be transcribed
into non-coding RNAs. One category of non-coding RNAs is classified as long non-coding …

The Implications of the Long Non-Coding RNA NEAT1 in Non-Cancerous Diseases

F Prinz, A Kapeller, M Pichler, C Klec - International journal of molecular …, 2019 - mdpi.com
Long non-coding RNAs (lncRNAs) are involved in a variety of biological and cellular
processes as well as in physiologic and pathophysiologic events. This review summarizes …

LncRNA NEAT1 in paraspeckles: a structural scaffold for cellular DNA damage response systems?

E Taiana, D Ronchetti, K Todoerti, L Nobili, P Tassone… - Non-coding RNA, 2020 - mdpi.com
Nuclear paraspeckle assembly transcript 1 (NEAT1) is a long non-coding RNA (lncRNA)
reported to be frequently deregulated in various types of cancers and neurodegenerative …

[HTML][HTML] Neat1 regulates oxidized low-density lipoprotein-induced inflammation and lipid uptake in macrophages via paraspeckle formation

N Huang‑Fu, JS Cheng, Y Wang… - Molecular …, 2018 - spandidos-publications.com
Oxidized low-density lipoprotein (oxLDL) induces macrophage inflammation and lipid
uptake, and serves important roles in the development of atherosclerosis. The long non …