[HTML][HTML] Docosahexaenoic acid alters the size and distribution of cell surface microdomains
RS Chapkin, N Wang, YY Fan, JR Lupton… - Biochimica et Biophysica …, 2008 - Elsevier
We recently generated nutritional data suggesting that chemoprotective dietary n-3
polyunsaturated fatty acids (n-3 PUFA) are capable of displacing acylated proteins from lipid …
polyunsaturated fatty acids (n-3 PUFA) are capable of displacing acylated proteins from lipid …
n− 3 PUFA and membrane microdomains: a new frontier in bioactive lipid research
DWL Ma, J Seo, KC Switzer, YY Fan… - The Journal of nutritional …, 2004 - Elsevier
In recent years, our understanding of the plasma membrane has changed considerably as
our knowledge of lipid microdomains has expanded. Lipid microdomains include structures …
our knowledge of lipid microdomains has expanded. Lipid microdomains include structures …
Biophysical and biochemical mechanisms by which dietary N-3 polyunsaturated fatty acids from fish oil disrupt membrane lipid rafts
SR Shaikh - The Journal of nutritional biochemistry, 2012 - Elsevier
N-3 polyunsaturated fatty acids (PUFAs) from fish oil exert their functional effects by targeting
multiple mechanisms. One mechanism to emerge in the past decade is the ability of n-3 …
multiple mechanisms. One mechanism to emerge in the past decade is the ability of n-3 …
[HTML][HTML] Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid rafts
YY Fan, DN McMurray, LH Ly, RS Chapkin - The Journal of nutrition, 2003 - Elsevier
In vitro evidence indicates that (n-3) polyunsaturated fatty acids (PUFA) suppress T-cell
activation in part by displacing proteins from lipid rafts, specialized regions within the plasma …
activation in part by displacing proteins from lipid rafts, specialized regions within the plasma …
Effects of dietary n− 3 polyunsaturated fatty acids on T-cell membrane composition and function
KC Switzer, DN McMurray, RS Chapkin - Lipids, 2004 - Springer
Dietary n− 3 PUFA have been shown to attenuate T-cell-mediated inflammation, in part, by
suppressing T-cell activation and proliferation. n− 3 PUFA have also been shown to promote …
suppressing T-cell activation and proliferation. n− 3 PUFA have also been shown to promote …
Docosahexaenoic and eicosapentaenoic acids segregate differently between raft and nonraft domains
JA Williams, SE Batten, M Harris, BD Rockett… - Biophysical journal, 2012 - cell.com
Omega-3 polyunsaturated fatty acids (n-3 PUFA), enriched in fish oils, are increasingly
recognized to have potential benefits for treating many human afflictions. Despite the …
recognized to have potential benefits for treating many human afflictions. Despite the …
n‐3 PUFA Alter caveolae lipid composition and resident protein localization in mouse colon
DWL Ma, J Seo, LA Davidson, ES Callaway… - The FASEB …, 2004 - Wiley Online Library
Caveolae, by virtue of their unique lipid environment, serve as signaling platforms that
regulate cellular events. Perturbations in caveolae lipid composition have been shown in …
regulate cellular events. Perturbations in caveolae lipid composition have been shown in …
Bioactive dietary long-chain fatty acids: emerging mechanisms of action
RS Chapkin, DN McMurray, LA Davidson… - British Journal of …, 2008 - cambridge.org
The plasma membranes of all eukaryotic cells contain heterogeneous self-organising
intrinsically unstable liquid ordered domains or lipid assemblies in which key signal …
intrinsically unstable liquid ordered domains or lipid assemblies in which key signal …
Dietary docosahexaenoic acid suppresses T cell protein kinase Cθ lipid raft recruitment and IL-2 production
YY Fan, LH Ly, R Barhoumi, DN McMurray… - The Journal of …, 2004 - journals.aai.org
To date, the proximal molecular targets through which dietary n-3 polyunsaturated fatty acids
(PUFA) suppress the inflammatory process have not been elucidated. Because cholesterol …
(PUFA) suppress the inflammatory process have not been elucidated. Because cholesterol …
Membrane lipid raft organization is uniquely modified by n-3 polyunsaturated fatty acids
HF Turk, RS Chapkin - Prostaglandins, Leukotrienes and Essential Fatty …, 2013 - Elsevier
Fish oil, enriched in bioactive n-3 polyunsaturated fatty acids (PUFA), has been shown to
play a role in prevention of colon cancer. The effects of n-3 PUFA are pleiotropic and …
play a role in prevention of colon cancer. The effects of n-3 PUFA are pleiotropic and …