By using imaging spectrophotometry with paired images in the 200‐to 280‐nm wavelength
range, we have directly mapped intracellular nucleic acid and protein distributions across a …

The organization of proteins in space and time is essential to their function. To accurately
quantify subcellular protein characteristics in a population of cells with regard for the …

We present measurements by deep‐ultraviolet mass mapping of nucleic acid (NA) and
protein for five commonly cultured and three primary cell types. The dry mass distribution at …

In this column, I briefly reflect on the manner in which automated analysis of the subcellular
distribution of proteins (location proteomics) is relevant to the field of cytomics. There are …

We developed a deep-ultraviolet (UV) microscope capable of imaging cell mitosis and
motility at 280 nm for 45 min with minimal UV-induced toxicity, and for 6 h before the onset of …

Using synchrotron radiation as an ultra-bright infrared source, we have been able to map the
distributions of functional groups such as proteins, lipids, and nucleic acids inside a single …

The full understanding of cellular functions requires information about protein numbers for
various biomolecular assemblies and their dynamics, which can be partly accessed by …

Fluorescent probes offer insight into the highly localized and rapid molecular events that
underlie cell function. However, methods are required that can efficiently transform the …

Intracellular protein concentration is an essential cell characteristic, which manifests itself
through the refractive index. The latter can be measured from two or more mutually …

Proteomics, the large scale identification and characterization of many or all proteins
expressed in a given cell type, has become a major area of biological research. In addition …