Carbohydrate vaccines: developing sweet solutions to sticky situations?

RD Astronomo, DR Burton - Nature reviews Drug discovery, 2010 - nature.com
Recent technological advances in glycobiology and glycochemistry are paving the way for a
new era in carbohydrate vaccine design. This is enabling greater efficiency in the …

[HTML][HTML] Recent advances and future perspectives on carbohydrate-based cancer vaccines and therapeutics

C Sorieul, F Papi, F Carboni, S Pecetta… - Pharmacology & …, 2022 - Elsevier
Carbohydrates are abundantly expressed on the surface of both eukaryotic and prokaryotic
cells, often as post translational modifications of proteins. Glycoproteins are recognized by …

Carbohydrate-based vaccines: challenges and opportunities

YL Huang, CY Wu - Expert Review of Vaccines, 2010 - Taylor & Francis
Advances in the synthesis of oligo-or polysaccharides and new technologies developed in
glycobiology studies have opened a new avenue in carbohydrate vaccine design. In …

Discovery of semi-and fully-synthetic carbohydrate vaccines against bacterial infections using a medicinal chemistry approach: focus review

PH Seeberger - Chemical Reviews, 2021 - ACS Publications
The glycocalyx, a thick layer of carbohydrates, surrounds the cell wall of most bacterial and
parasitic pathogens. Recognition of these unique glycans by the human immune system …

Chemical biology approaches to designing defined carbohydrate vaccines

C Anish, B Schumann, CL Pereira, PH Seeberger - Chemistry & biology, 2014 - cell.com
Carbohydrate antigens have shown promise as important targets for developing effective
vaccines and pathogen detection strategies. Modifying purified microbial glycans through …

Entirely carbohydrate-based vaccines: an emerging field for specific and selective immune responses

S Nishat, PR Andreana - Vaccines, 2016 - mdpi.com
Carbohydrates are regarded as promising targets for vaccine development against
infectious disease because cell surface glycans on many infectious agents are attributed to …

Recent advances on smart glycoconjugate vaccines in infections and cancer

M Anderluh, F Berti, A Bzducha‐Wróbel… - The FEBS …, 2022 - Wiley Online Library
Vaccination is one of the greatest achievements in biomedical research preventing death
and morbidity in many infectious diseases through the induction of pathogen‐specific …

Carbohydrate based vaccines

B Kuberan, RJ Linhardt - Current Organic Chemistry, 2000 - ingentaconnect.com
Vaccination is the most cost-efficient and the most powerful medical intervention in the
control, prevention and eradication of many diseases that affect human population. Capsular …

Clustered carbohydrates in synthetic vaccines

F Peri - Chemical Society Reviews, 2013 - pubs.rsc.org
Are there general rules to obtain efficient immunization against carbohydrate antigens?
Thanks to technological advances in glycobiology and glycochemistry we entered a new era …

Recent development in carbohydrate based anticancer vaccines

Z Yin, X Huang - Journal of Carbohydrate Chemistry, 2012 - Taylor & Francis
The development of carbohydrate-based anticancer vaccines is of high current interest.
Herein, the latest development in this exciting field is reviewed. After a general introduction …