Oxidative stress contributes to dysfunction of glial cells in the optic nerve head (ONH).
However, the biological basis of the precise functional role of mitochondria in this …

Glaucoma is a worldwide leading cause of irreversible vision loss characterized by
progressive death of retinal ganglion cells (RGCs). In the course of glaucoma, RGC death …

Abstract Coenzyme Q10 (CoQ10) acts by scavenging reactive oxygen species to protect
neuronal cells against oxidative stress in neurodegenerative diseases. The present study …

Purpose.: To test whether a diet supplemented with coenzyme Q10 (CoQ 10) ameliorates
glutamate excitotoxicity and oxidative stress–mediated retinal ganglion cell (RGC) …

Oxidative stress is a major component of harmful cascades activated in neurodegenerative
disorders. Coenzyme Q10 (CoQ10), an essential component in the mitochondrial respiratory …

Abstract Coenzyme Q10 (CoQ 10) acts by scavenging reactive oxygen species for protecting
neuronal cells against oxidative stress in neurodegenerative diseases. We tested whether a …

Abstract Coenzyme Q10 (CoQ10) is a mitochondrial-targeted antioxidant with known
neuroprotective activity. Its ocular effects when co-solubilised with α–tocopherol …

Recent studies support a role for excitotoxicity in the development of retinal ganglion cell
(RGC) damage in subjects suffering from glaucoma. Coenzyme Q10 (CoQ10), an essential …

Neuronal cells depend on mitochondrial oxidative phosphorylation for most of their energy
needs and therefore are at a particular risk for oxidative stress. Mitochondria play an …

Background: Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative
phosphorylation by serving as an electron carrier in the respiratory electron transport chain …