Gene–obesogenic environment interactions in the UK Biobank study
Background: Previous studies have suggested that modern obesogenic environments
accentuate the genetic risk of obesity. However, these studies have proven controversial as …
accentuate the genetic risk of obesity. However, these studies have proven controversial as …
Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status
M Rask-Andersen, T Karlsson, WE Ek… - PLoS genetics, 2017 - journals.plos.org
Previous genome-wide association studies (GWAS) have identified hundreds of genetic loci
to be associated with body mass index (BMI) and risk of obesity. Genetic effects can differ …
to be associated with body mass index (BMI) and risk of obesity. Genetic effects can differ …
The importance of gene–environment interactions in human obesity
The worldwide obesity epidemic has been mainly attributed to lifestyle changes. However,
who becomes obese in an obesity-prone environment is largely determined by genetic …
who becomes obese in an obesity-prone environment is largely determined by genetic …
Quantifying the impact of genes on body mass index during the obesity epidemic: longitudinal findings from the HUNT Study
M Brandkvist, JH Bjørngaard, RA Ødegård, BO Åsvold… - bmj, 2019 - bmj.com
Objectives To study the trajectories of body mass index (BMI) in Norway over five decades
and to assess the differential influence of the obesogenic environment on BMI according to …
and to assess the differential influence of the obesogenic environment on BMI according to …
The contribution of genetics and environment to obesity
Background Obesity is a global health problem mainly attributed to lifestyle changes such as
diet, low physical activity or socioeconomics factors. However, several evidences …
diet, low physical activity or socioeconomics factors. However, several evidences …
Interaction between genes and lifestyle factors on obesity: Nutrition Society Silver Medal Lecture
A Marti, MA Martinez-González… - Proceedings of the …, 2008 - cambridge.org
Obesity originates from a failure of the body-weight control systems, which may be affected
by changing environmental influences. Basically, the obesity risk depends on two important …
by changing environmental influences. Basically, the obesity risk depends on two important …
Gene-environment interactions and obesity: recent developments and future directions
Obesity, a major public health concern, is a multifactorial disease caused by both
environmental and genetic factors. Although recent genome-wide association studies have …
environmental and genetic factors. Although recent genome-wide association studies have …
Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study
Background We have previously shown that multiple genetic loci identified by genome-wide
association studies (GWAS) increase the susceptibility to obesity in a cumulative manner. It …
association studies (GWAS) increase the susceptibility to obesity in a cumulative manner. It …
Gene× physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry
Numerous obesity loci have been identified using genome-wide association studies. A UK
study indicated that physical activity may attenuate the cumulative effect of 12 of these loci …
study indicated that physical activity may attenuate the cumulative effect of 12 of these loci …
Increasing genetic variance of body mass index during the Swedish obesity epidemic
B Rokholm, K Silventoinen, P Tynelius, M Gamborg… - PloS one, 2011 - journals.plos.org
Background and Objectives There is no doubt that the dramatic worldwide increase in
obesity prevalence is due to changes in environmental factors. However, twin and family …
obesity prevalence is due to changes in environmental factors. However, twin and family …