The source of high signal cooperativity in bacterial chemosensory arrays
GE Piñas, V Frank, A Vaknin… - Proceedings of the …, 2016 - National Acad Sciences
The Escherichia coli chemosensory system consists of large arrays of transmembrane
chemoreceptors associated with a dedicated histidine kinase, CheA, and a linker protein …
chemoreceptors associated with a dedicated histidine kinase, CheA, and a linker protein …
Core unit of chemotaxis signaling complexes
M Li, GL Hazelbauer - … of the National Academy of Sciences, 2011 - National Acad Sciences
Bacterial chemoreceptors, histidine kinase CheA, and coupling protein CheW form clusters
of chemotaxis signaling complexes. In signaling complexes kinase activity is enhanced …
of chemotaxis signaling complexes. In signaling complexes kinase activity is enhanced …
Defining a key receptor–CheA kinase contact and elucidating its function in the membrane-bound bacterial chemosensory array: a disulfide mapping and TAM-IDS …
KN Piasta, CJ Ulliman, PF Slivka, BR Crane… - Biochemistry, 2013 - ACS Publications
The three core components of the ubiquitous bacterial chemosensory array the
transmembrane chemoreceptor, the histidine kinase CheA, and the adaptor protein CheW …
transmembrane chemoreceptor, the histidine kinase CheA, and the adaptor protein CheW …
Hexameric rings of the scaffolding protein CheW enhance response sensitivity and cooperativity in Escherichia coli chemoreceptor arrays
The Escherichia coli chemoreceptor array is a supramolecular assembly that enables cells
to respond to extracellular cues dynamically and with great precision and sensitivity. In the …
to respond to extracellular cues dynamically and with great precision and sensitivity. In the …
Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins
A Briegel, X Li, AM Bilwes, KT Hughes… - Proceedings of the …, 2012 - National Acad Sciences
Chemoreceptor arrays are supramolecular transmembrane machines of unknown structure
that allow bacteria to sense their surroundings and respond by chemotaxis. We have …
that allow bacteria to sense their surroundings and respond by chemotaxis. We have …
[HTML][HTML] Regulation of the chemotaxis histidine kinase CheA: A structural perspective
Bacteria sense and respond to their environment through a highly conserved assembly of
transmembrane chemoreceptors (MCPs), the histidine kinase CheA, and the coupling …
transmembrane chemoreceptors (MCPs), the histidine kinase CheA, and the coupling …
The 3.2 Å resolution structure of a receptor: CheA: CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial …
X Li, AD Fleetwood, C Bayas, AM Bilwes… - Biochemistry, 2013 - ACS Publications
Bacterial chemosensory arrays are composed of extended networks of chemoreceptors
(also known as methyl-accepting chemotaxis proteins, MCPs), the histidine kinase CheA …
(also known as methyl-accepting chemotaxis proteins, MCPs), the histidine kinase CheA …
His-tag-mediated dimerization of chemoreceptors leads to assembly of functional nanoarrays
Transmembrane chemotaxis receptors are found in bacteria in extended hexagonal arrays
stabilized by the membrane and by cytosolic binding partners, the kinase CheA and …
stabilized by the membrane and by cytosolic binding partners, the kinase CheA and …
Structure, function, and on–off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide …
The ultrasensitive, ultrastable bacterial chemosensory array of Escherichia coli and
Salmonella typhimurium is representative of the large, conserved family of sensory arrays …
Salmonella typhimurium is representative of the large, conserved family of sensory arrays …
Insights into the organization and dynamics of bacterial chemoreceptor clusters through in vivo crosslinking studies
CA Studdert, JS Parkinson - Proceedings of the National …, 2005 - National Acad Sciences
The team signaling model for bacterial chemoreceptors proposes that receptor dimers of
different detection specificities form mixed trimers of dimers that bind the cytoplasmic …
different detection specificities form mixed trimers of dimers that bind the cytoplasmic …