Behavioral changes in male mice fed a high-fat diet are associated with IL-1β expression in specific brain regions
CP Almeida-Suhett, A Graham, Y Chen, P Deuster - Physiology & behavior, 2017 - Elsevier
Abstract High-fat diet (HFD)-induced obesity is associated with not only increased risk of
metabolic and cardiovascular diseases, but cognitive deficit, depression and anxiety …
metabolic and cardiovascular diseases, but cognitive deficit, depression and anxiety …
Dietary fat exacerbates postprandial hypothalamic inflammation involving glial fibrillary acidic protein‐positive cells and microglia in male mice
In humans, obesity is associated with brain inflammation, glial reactivity, and immune cells
infiltration. Studies in rodents have shown that glial reactivity occurs within 24 hr of high‐fat …
infiltration. Studies in rodents have shown that glial reactivity occurs within 24 hr of high‐fat …
Effects of high-fat diet and chronic mild stress on depression-like behaviors and levels of inflammatory cytokines in the hippocampus and prefrontal cortex of rats
W Wang, J Yang, J Xu, H Yu, Y Liu, R Wang, RCM Ho… - Neuroscience, 2022 - Elsevier
Obesity and depression tend to co-occur, and obese patients with chronic low-grade
inflammation have a higher risk of developing depression. However, mechanisms …
inflammation have a higher risk of developing depression. However, mechanisms …
Fasting Induces an Anti‐Inflammatory Effect on the Neuroimmune System Which a High‐Fat Diet Prevents
DN Lavin, JJ Joesting, GS Chiu, ML Moon, J Meng… - …, 2011 - Wiley Online Library
The neuroimmunological and behavioral consequences of a high‐fat diet (HFD) are not well
delineated. This is especially true when short term (24 h) fasting is used as a physiologic …
delineated. This is especially true when short term (24 h) fasting is used as a physiologic …
High-fat diet enhances working memory in the Y-maze test in male C57BL/6J mice with less anxiety in the elevated plus maze test
K Yoshizaki, M Asai, T Hara - Nutrients, 2020 - mdpi.com
Obesity is characterized by massive adipose tissue accumulation and is associated with
psychiatric disorders and cognitive impairment in human and animal models. However, it is …
psychiatric disorders and cognitive impairment in human and animal models. However, it is …
Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats
SSR Noronha, PM Lima, GSV Campos… - Brain, Behavior, and …, 2019 - Elsevier
Overweight and obesity are a worldwide pandemic affecting billions of people. These
conditions have been associated with a chronic low-grade inflammatory state that is …
conditions have been associated with a chronic low-grade inflammatory state that is …
Brain tumor necrosis factor-α mediates anxiety-like behavior in a mouse model of severe obesity
C Fourrier, C Bosch-Bouju, R Boursereau… - Brain, behavior, and …, 2019 - Elsevier
Although the high prevalence of anxiety in obesity increasingly emerges as significant risk
factor for related severe health complications, the underlying pathophysiological …
factor for related severe health complications, the underlying pathophysiological …
High-fat diet consumption disrupts memory and primes elevations in hippocampal IL-1β, an effect that can be prevented with dietary reversal or IL-1 receptor …
JL Sobesky, RM Barrientos, S Henning… - Brain, behavior, and …, 2014 - Elsevier
Abstract High-fat diet (HFD)-induced obesity is reaching worldwide proportions. In addition
to causing obesity, HFDs also induce a variety of health disorders, which includes cognitive …
to causing obesity, HFDs also induce a variety of health disorders, which includes cognitive …
Cognitive impairment following high fat diet consumption is associated with brain inflammation
PJ Pistell, CD Morrison, S Gupta, AG Knight… - Journal of …, 2010 - Elsevier
C57Bl/6 mice were administered a high fat, Western diet (WD, 41% fat) or a very high fat lard
diet (HFL, 60% fat), and evaluated for cognitive ability using the Stone T-maze and for …
diet (HFL, 60% fat), and evaluated for cognitive ability using the Stone T-maze and for …
Chronic high fat feeding increases anxiety-like behaviour and reduces transcript abundance of glucocorticoid signalling genes in the hippocampus of female rats
S Sivanathan, K Thavartnam, S Arif, T Elegino… - Behavioural brain …, 2015 - Elsevier
The consumption of diets high in saturated fats and obesity have been associated with
impaired physical and mental health. Previous studies indicate that chronic high fat diet …
impaired physical and mental health. Previous studies indicate that chronic high fat diet …