Background Docetaxel (DTX) has been used to treat numerous types of cancers. It's poor
solubility, serious side effects, and multi-drug resistance (MDR) limits its use in cancer …

Docetaxel (DTX) has poor solubility, serious side effects, and multi-drug resistance (MDR)
limiting its use in cancer treatment. Hence, the present study aimed to formulate and develop …

Purpose Camptothecin has poor solubility, high systemic toxicity, and intrinsic structural
instability. To deal with these challenges, present research aimed to develop camptothecin …

In this work, novel docetaxel (DTX)-loaded Tween 80-free Pluronic P123 (P123) micelles
with improved therapeutic effect were developed. The freeze-dried DTX-loaded P123 …

The aim of this work was to establish a novel polymeric mixed micelle composed of Pluronic
P105 and F127 copolymers loaded with the poorly soluble antitumor drug docetaxel (DTX) …

Docetaxel (DOC) produces anti-tumor effects by inducing apoptosis and inhibiting cell
growth. However, its clinical application is limited by its hydrophobicity and low …

In this work, docetaxel (DTX) was encapsulated in monomethoxy poly (ethylene glycol)-poly
(ε-caprolactone)(mPEG-PCL) micelles and monomethoxy poly (ethylene glycol)-poly (D, L …

Purpose Methotrexate (MTX), a potent anticancer drug, shows low oral bioavailability due to
its low aqueous solubility and permeability. Moreover, its multidrug resistance (MDR) in …

Self-assembled polymeric micelles have been widely applied in drug delivery systems. In
this study, we found that pH value of micellar system solution was the decisive factor of …

Introductions Ovarian cancer is a stubborn malignancy of gynecological system with a high
mortality rate. Docetaxel (DTX), the second-generation of anti-tumor drug Taxane, has …