In this study, we used diffuse optics to address the need for non-invasive, continuous
monitoring of cerebral physiology following traumatic brain injury (TBI). We combined …

The authors' aim is to assess and quantitatively measure brain hemodynamic and
morphological variations during closed-head injury (CHI) in mice using orthogonal diffuse …

We used a nonimpact inertial rotational model of a closed head injury in neonatal piglets to
simulate the conditions following traumatic brain injury in infants. Diffuse optical techniques …

Optical techniques have gained substantial interest over the past four decades for
biomedical imaging due to their unique advantages, which may suggest their use as …

Rapid detection of ischemic conditions at the bedside can improve treatment of acute brain
injury. In this observational study of 11 critically ill brain-injured adults, we employed a …

Prevention of secondary damage is an important goal in the treatment of severe
neurological conditions, such as major head trauma or stroke. However, there is currently a …

Survivors of severe brain injury may require care in a neurointensive care unit (neuro-ICU),
where the brain is vulnerable to secondary brain injury. Thus, there is a need for …

Nearly half a million children and young adults are affected by traumatic brain injury each
year in the United States. Although adequate cerebral blood flow (CBF) is essential to …

We present an overview of the wide range of potential applications of optical methods for
monitoring traumatic brain injury. The MEDLINE database was electronically searched with …

Near-infrared spectroscopy (NIRS) and diffuse optical imaging (DOI) are finding widespread
application in the study of human brain activation, motivating further application-specific …