With recent advances in nanotechnology and therapeutic nucleic acids (TNAs), various
nucleic acid nanoparticles (NANPs) have demonstrated great promise in diagnostics and …

RNAi-based technologies have shown biomedical potential; however, safe and efficient
delivery of RNA remains a barrier for their broader clinical applications. Nucleic acid …

Simple Summary Nucleic acid drugs provide novel therapeutic modalities with
characteristics that differ from those of small molecules and antibodies. In this review, I focus …

Many aspects of intercellular communication are mediated through “sending” and
“receiving” packets of information via the secretion and subsequent receptor-mediated …

Exosomes are biological membrane vesicles measuring 30 to 100nm. They contain an
abundance of small molecules like tetraspanins, receptors for targeting and adhesion, lipids …

Exosomes are a subtype of membrane vesicle released from the endocytic compartment of
live cells. They play an important role in endogenous cell-to-cell communication. Previously …

In the last few decades, RNA-based drugs have emerged as a promising candidate to
specifically target and modulate disease-relevant genes to cure genetic defects. The key to …

Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …

Exosomes are naturally occurring extracellular vesicles released by most mammalian cells
in all body fluids. Exosomes are known as key mediators in cell‐cell communication and …

Exosomes are natural delivery vehicles because of their original feature such as low
immunogenicity, excellent biocompatibility, and migration capability. Engineering exosomes …