Mesenchymal stem cells (MSCs) are promising candidates for tissue regeneration and
disease treatment. However, long-term in vitro passaging leads to stemness loss of MSCs …

Although stem cells have emerged as promising sources for regenerative medicine, there
are many potential safety hazards for their clinical application, including tumorigenicity, an …

Accumulation of senescent bone marrow‐derived mesenchymal stem cells (BMMSCs) has
led to an age‐related bone loss. However, the role of stem cell senescence in estrogen …

Postmenopausal osteoporosis (OP) is one of the most common bone diseases that affects
millions of aging women. Reduced osteogenesis and increased oxidative stress have been …

Mesenchymal stem cells (MSCs) are promising candidates for tissue regeneration and
disease treatment. However, long‐term in vitro culture results in loss of MSC stemness. The …

Background Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in
regenerative medicine. However, the efficiency of MSC transplantation and survival of …

Objective Mesenchymal stem cells (MSC) from various sources have the potentials to
positively affect regenerative medicine. Furthermore, pre-conditioning strategies with …

Background: Previous studies reported that melatonin exerts its effect on mesenchymal stem
cell (MSC) survival and differentiation into osteogenic and adipogenic lineage. In the current …

Both self-renewal and lineage-specific differentiation of mesenchymal stem cells (MSCs) are
triggered by their in vivo microenvironment including the extracellular matrix (ECM) and …

Background Osteoarthritis (OA) is a widespread arthritic disease and a primary cause of
disability. Increasing evidence suggests that inflammation has a pivotal part in its …