The FGF/FGFR system in the physiopathology of the prostate gland
Fibroblast growth factors (FGFs) are a family of proteins possessing paracrine, autocrine, or
endocrine functions in a variety of biological processes, including embryonic development …
endocrine functions in a variety of biological processes, including embryonic development …
FGF signalling in prostate development, tissue homoeostasis and tumorigenesis
Y Lin, F Wang - Bioscience reports, 2010 - portlandpress.com
The FGFs (fibroblast growth factors) regulate a broad spectrum of biological activities by
activating transmembrane FGFR (FGF receptor) tyrosine kinases and their coupled …
activating transmembrane FGFR (FGF receptor) tyrosine kinases and their coupled …
[HTML][HTML] FGF signaling in prostate tumorigenesis—new insights into epithelial-stromal interactions
C Abate-Shen, MM Shen - Cancer Cell, 2007 - cell.com
Members of the fibroblast growth factor (FGF) family are believed to play critical roles during
organogenesis and carcinogenesis via signaling between epithelial and stromal …
organogenesis and carcinogenesis via signaling between epithelial and stromal …
[HTML][HTML] The role of fibroblast growth factors and their receptors in prostate cancer
B Kwabi-Addo, M Ozen… - Endocrine-related cancer, 2004 - erc.bioscientifica.com
Prostate cancer is the most common malignancy in men in the USA and the second leading
cause of cancer deaths. Fibroblast growth factors (FGFs), including FGF1 (acidic FGF), FGF2 …
cause of cancer deaths. Fibroblast growth factors (FGFs), including FGF1 (acidic FGF), FGF2 …
Role of epithelial cell fibroblast growth factor receptor substrate 2α in prostate development, regeneration and tumorigenesis
Y Zhang, J Zhang, Y Lin, Y Lan, C Lin, JW Xuan… - 2008 - journals.biologists.com
The fibroblast growth factor (FGF) regulates a broad spectrum of biological activities by
activation of transmembrane FGF receptor (FGFR) tyrosine kinases and their coupled …
activation of transmembrane FGF receptor (FGFR) tyrosine kinases and their coupled …
Fibroblast growth factors in development and cancer: insights from the mammary and prostate glands
KL Schwertfeger - Current drug targets, 2009 - ingentaconnect.com
The fibroblast growth factor (FGF) family is comprised of 22 ligands that bind and activate
several FGF receptor (FGFR) isoforms. Critical roles for FGFs and FGFRs have been well …
several FGF receptor (FGFR) isoforms. Critical roles for FGFs and FGFRs have been well …
Down‐regulation of (IIIb) and (IIIc) isoforms of fibroblast growth factor receptor 2 (FGFR2) is associated with malignant progression in human prostate
B Naimi, A Latil, G Fournier, P Mangin… - The …, 2002 - Wiley Online Library
BACKGROUND Fibroblast growth factors (FGFs) and their receptors (FGFRs) have a critical
function in the cellular stroma/epithelium interaction for the development and homeostasis of …
function in the cellular stroma/epithelium interaction for the development and homeostasis of …
Restoration of fibroblast growth factor receptor2 suppresses growth and tumorigenicity of malignant human prostate carcinoma PC‐3 cells
H Yasumoto, A Matsubara, K Mutaguchi, T Usui… - The …, 2004 - Wiley Online Library
BACKGROUND Fibroblast growth factors (FGFs) and their receptors (FGFRs) expedite
stromal–epithelial communication in development and homeostasis of the human prostate …
stromal–epithelial communication in development and homeostasis of the human prostate …
Androgen receptor expression induces FGF2, FGF‐binding protein production, and FGF2 release in prostate carcinoma cells: role of FGF2 in growth, survival, and …
P Rosini, L Bonaccorsi, E Baldi, C Chiasserini… - The …, 2002 - Wiley Online Library
BACKGROUND Alterations in fibroblast growth factors (FGFs) production and/or FGF
receptors expression have been described to play key roles in prostate tumor progression …
receptors expression have been described to play key roles in prostate tumor progression …
Fibroblast growth factor 2: its structure and property, paracrine function, tumor angiogenesis, and prostate-related mitogenic and oncogenic functions
JK Dow, RWV White - Urology, 2000 - goldjournal.net
(FGF2), or basic FGF. It is synthesized mainly by stromal fibroblasts and functions in both an
autocrine and paracrine fashion. When prostate cancer converts to an invasive phenotye …
autocrine and paracrine fashion. When prostate cancer converts to an invasive phenotye …