The use of TPGS in drug delivery systems to overcome biological barriers

MT Luiz, LD Di Filippo, RC Alves, VHS Araújo… - European Polymer …, 2021 - Elsevier
Nanotechnology has been applied in the medicine field to improve the treatment of a wide
range of diseases. However, to reach the nanomedicines delivery to desirable target tissue …

Vitamin E TPGS as a molecular biomaterial for drug delivery

Z Zhang, S Tan, SS Feng - Biomaterials, 2012 - Elsevier
d-α-tocopheryl polyethylene glycol succinate (Vitamin E TPGS, or simply TPGS) is a water-
soluble derivative of natural Vitamin E, which is formed by esterification of Vitamin E …

Emerging advances in P-glycoprotein inhibitory nanomaterials for drug delivery

L Kou, R Sun, YD Bhutia, Q Yao… - Expert opinion on drug …, 2018 - Taylor & Francis
ABSTRACT Introduction: P-glycoprotein 1 (P-gp) pumps out many foreign/toxic substances
out of the cells, including intracellular drugs, causing multidrug resistance (MDR) and …

Vitamin E D-α-tocopheryl polyethylene glycol 1000 succinate-based nanomedicine

Z Zhang, L Mei, SS Feng - Nanomedicine, 2012 - Future Medicine
Molecular biomaterials, meaning biocompatible and/or biodegradable materials that are
molecularly synthesized or engineered, provide the material basis for and thus play a key …

[HTML][HTML] Vitamin E TPGS-based nanomedicine, nanotheranostics, and targeted drug delivery: past, present, and future

AK Mehata, A Setia, AK Malik, R Hassani, HG Dailah… - Pharmaceutics, 2023 - mdpi.com
It has been seventy years since a water-soluble version of vitamin E called tocophersolan
(also known as TPGS) was produced; it was approved by USFDA in 1998 as an inactive …

Application of TPGS in polymeric nanoparticulate drug delivery system

L Mu, PH Seow - Colloids and Surfaces B: Biointerfaces, 2006 - Elsevier
d-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) has great potential in
pharmacology and nanotechnology. The present work investigated the molecular behaviour …

Nanocarriers based on vitamin E-TPGS: Design principle and molecular insights into improving the efficacy of anticancer drugs

S Rathod, P Bahadur, S Tiwari - International Journal of Pharmaceutics, 2021 - Elsevier
Abstract α-Tocopheryl polyethylene glycol succinate (vitamin E-TPGS or TPGS) is a nonionic
amphiphile synthesized by the esterification of vitamin E succinate. It has been categorized …

Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles

R De, MK Mahata, KT Kim - Advanced Science, 2022 - Wiley Online Library
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

The applications of Vitamin E TPGS in drug delivery

Y Guo, J Luo, S Tan, BO Otieno, Z Zhang - European journal of …, 2013 - Elsevier
d-α-Tocopheryl polyethylene glycol 1000 succinate (simply TPGS or Vitamin E TPGS) is
formed by the esterification of Vitamin E succinate with polyethylene glycol 1000. As novel …

[HTML][HTML] Recent advances in the application of vitamin E TPGS for drug delivery

C Yang, T Wu, Y Qi, Z Zhang - Theranostics, 2018 - ncbi.nlm.nih.gov
D-ɑ-tocopheryl polyethylene glycol succinate (Vitamin E TPGS or TPGS) has been
approved by FDA as a safe adjuvant and widely used in drug delivery systems. The …