Background Suitable in vitro models are needed to investigate urothelial epithelial to
mesenchymal transition (EMT) and pro-fibrogenesis phenotype in bladder pain …

Objectives To examine the correlation among bladder inflammation, angiogenesis, fibrosis
and urothelial denudation in biopsied bladder specimens, and O'Leary‐Sant symptom …

What's known on the subject? and What does the study add? Interstitial cystitis/painful
bladder syndrome (IC/PBS) is considered to result from long‐standing inflammation of the …

Although the cause of interstitial cystitis/painful bladder syndrome (IC/PBS) remains
unknown, autoimmune involvement has been strongly suggested to be a contributing factor …

Given the recent evidence in the clinical application of regenerative medicine, mostly on
integumentary systems, we focused our interests on recent bladder regeneration …

Objectives To explore the expression of cytoskeletal and cell proliferation proteins in
urothelial cells of patients diagnosed with various clinical subtypes of interstitial …

The aim of this study was to investigate the expression levels of sensory receptors,
inflammatory proteins, and pro-apoptotic proteins in the urothelium of non-Hunner's …

OBJECTIVE: To investigate whether bladder inflammation could directly modulate the
signaling pathway of increased urothelial cell apoptosis in interstitial cystitis/painful bladder …

Objectives: Although evidence supports a role for inflammation in interstitial cystitis/bladder
pain syndrome (IC/BPS), the mechanism remains unknown. We determined whether …

The human bladder urothelium (BU) and bladder urothelial cells (BUCs) play an important
role in the normal functioning of bladder including bladder storage. Current evidence in …