Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) are
among the leading causes of mortality and poor health burden in the world. Both COPD and …

Background Exacerbations of chronic obstructive pulmonary disease result in increased
airway inflammation and accelerated disease progression. Viral exacerbations are …

Chronic obstructive pulmonary disease (COPD) is a chronic, complex, and heterogeneous
condition with significant mortality, morbidity, and socioeconomic burden. Given the …

Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous syndrome
that represents a major global health burden. COPD phenotypes have recently emerged …

COPD is a leading cause of mortality and morbidity worldwide and is associated with a high
socioeconomic burden. Current treatment includes the use of inhaled corticosteroids and …

Inflammation is a protective response to injury, but it can become chronic, leading to tissue
damage and disease. Cigarette smoke causes multiple inflammatory diseases, which …

This chronic inflammatory change and repetitive injury from tobacco smoke and other
exposures propagate a cascade of events, including airway remodeling, that results in fixed …

Interleukin (IL)-33 and its unique receptor, ST2, play a pivotal role in the immune response
to infection and stress. However, there have been conflicting reports of the role of IL-33 in …

Chronic obstructive pulmonary disease (COPD) affects more than 600 million adults
worldwide and accounts for 3 million deaths annually. Approximately 50% of the cases are …

Chronic obstructive pulmonary disease is characterized, in part, by chronic inflammation that
persists even after smoking cessation, suggesting that a failure to resolve inflammation plays …