mRNA vaccine development for emerging animal and zoonotic diseases

T Le, C Sun, J Chang, G Zhang, X Yin - Viruses, 2022 - mdpi.com
In the prevention and treatment of infectious diseases, mRNA vaccines hold great promise
because of their low risk of insertional mutagenesis, high potency, accelerated development …

Advances in mRNA vaccines for infectious diseases

C Zhang, G Maruggi, H Shan, J Li - Frontiers in immunology, 2019 - frontiersin.org
During the last two decades, there has been broad interest in RNA-based technologies for
the development of prophylactic and therapeutic vaccines. Preclinical and clinical trials have …

The key role of nucleic acid vaccines for one health

A Fomsgaard, MA Liu - Viruses, 2021 - mdpi.com
The ongoing SARS-CoV-2 pandemic has highlighted both the importance of One Health, ie,
the interactions and transmission of pathogens between animals and humans, and the …

mRNA as a transformative technology for vaccine development to control infectious diseases

G Maruggi, C Zhang, J Li, JB Ulmer, D Yu - Molecular Therapy, 2019 - cell.com
In the last two decades, there has been growing interest in mRNA-based technology for the
development of prophylactic vaccines against infectious diseases. Technological …

The promise of mRNA vaccines: a biotech and industrial perspective

NAC Jackson, KE Kester, D Casimiro, S Gurunathan… - npj Vaccines, 2020 - nature.com
Abstract mRNA technologies have the potential to transform areas of medicine, including the
prophylaxis of infectious diseases. The advantages for vaccines range from the acceleration …

Recent advances in the molecular design and delivery technology of mRNA for vaccination against infectious diseases

L Yang, L Tang, M Zhang, C Liu - Frontiers in Immunology, 2022 - frontiersin.org
Vaccines can prevent many millions of illnesses against infectious diseases and save
numerous lives every year. However, traditional vaccines such as inactivated viral and live …

mRNA vaccines in disease prevention and treatment

G Zhang, T Tang, Y Chen, X Huang… - Signal transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …

mRNA-based vaccines

F Kowalzik, D Schreiner, C Jensen, D Teschner… - Vaccines, 2021 - mdpi.com
Increases in the world's population and population density promote the spread of emerging
pathogens. Vaccines are the most cost-effective means of preventing this spread. Traditional …

Development of mRNA vaccines: scientific and regulatory issues

I Knezevic, MA Liu, K Peden, T Zhou, HN Kang - Vaccines, 2021 - mdpi.com
The global research and development of mRNA vaccines have been prodigious over the
past decade, and the work in this field has been stimulated by the urgent need for rapid …

Current developments and challenges of mRNA vaccines

J Chen, J Chen, Q Xu - Annual Review of Biomedical …, 2022 - annualreviews.org
mRNA vaccines have brought about a great revolution in the vaccine fields owing to their
simplicity and adaptability in antigen design, potential to induce both humoral and cell …