What does androgen receptor signaling pathway in sertoli cells during normal spermatogenesis tell us?

JM Wang, ZF Li, WX Yang - Frontiers in Endocrinology, 2022 - frontiersin.org
Androgen receptor signaling pathway is necessary to complete spermatogenesis in testes.
Difference between androgen binding location in Sertoli cell classifies androgen receptor …

The molecular mechanism of sex hormones on Sertoli cell development and proliferation

W Shah, R Khan, B Shah, A Khan, S Dil… - Frontiers in …, 2021 - frontiersin.org
Sustaining and maintaining the intricate process of spermatogenesis is liable upon
hormones and growth factors acting through endocrine and paracrine pathways. The Sertoli …

Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis

FD Ni, SL Hao, WX Yang - Cell death & disease, 2019 - nature.com
The functions of Sertoli cells in spermatogenesis have attracted much more attention
recently. Normal spermatogenesis depends on Sertoli cells, mainly due to their influence on …

Mechanisms of hormonal regulation of sertoli cell development and proliferation: a key process for spermatogenesis

GM Escott, LA da Rosa… - Current molecular …, 2014 - ingentaconnect.com
In adulthood, the main function of the testes is the production of male gametes. In this
process, Sertoli cells are essential for sustained spermatogenesis, providing the developing …

Molecular insights into hormone regulation via signaling pathways in Sertoli cells: With discussion on infertility and testicular tumor

FD Ni, SL Hao, WX Yang - Gene, 2020 - Elsevier
Spermatogenesis is a complex and elaborate differentiation process and is critical for male
fertility. The hypothalamic-pituitary–gonadal axis serves as a significant neuroendocrine …

The roles and regulation of Sertoli cells in fate determinations of spermatogonial stem cells and spermatogenesis

Y Hai, J Hou, Y Liu, Y Liu, H Yang, Z Li, Z He - Seminars in cell & …, 2014 - Elsevier
Spermatogenesis is a complex process by which spermatogonial stem cells (SSCs) self-
renew and differentiate into spermatozoa under the elaborate coordination of testicular …

[HTML][HTML] Non-genomic action of androgens is mediated by rapid phosphorylation and regulation of androgen receptor trafficking

Q Deng, Z Zhang, Y Wu, W Yu, J Zhang… - Cellular Physiology and …, 2017 - karger.com
Background: Testosterone is critical for maintaining spermatogenesis and male fertility. The
accomplishment of these processes requires the synergistic actions of the classical and non …

Molecular mechanisms and signaling pathways involved in sertoli cell proliferation

SB Meroni, MN Galardo, G Rindone, A Gorga… - Frontiers in …, 2019 - frontiersin.org
Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in
regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited …

Follicle-stimulating hormone signaling in Sertoli cells: a licence to the early stages of spermatogenesis

JM Wang, ZF Li, WX Yang, FQ Tan - Reproductive Biology and …, 2022 - Springer
Follicle-stimulating hormone signaling is essential for the initiation and early stages of
spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli …

[PDF][PDF] Regulation of spermatogonial stem cell self-renewal and spermatocyte meiosis by Sertoli cell signaling

SR Chen, YX Liu - 2015 - researchgate.net
Spermatogenesis is a continuous and productive process supported by the self-renewal and
differentiation of spermatogonial stem cells (SSCs), which arise from undifferentiated …