New Antiproliferative Triflavanone from Thymelaea hirsuta—Isolation, Structure Elucidation and Molecular Docking Studies
In this study isolates from Thymelaea hirsuta, a wild plant from the Sinai Peninsula of Egypt,
were identified and their selective cytotoxicity levels were evaluated. Phytochemical …
were identified and their selective cytotoxicity levels were evaluated. Phytochemical …
[HTML][HTML] Design, synthesis and biological evaluation of valepotriate derivatives as novel antitumor agents
Natural products remain the largest resources of lead compounds that can be used to
develop novel anticancer drug candidates. Based on deacetylisovaltratum, a natural product …
develop novel anticancer drug candidates. Based on deacetylisovaltratum, a natural product …
Crystal Structure Elucidation and Anticancer Studies of (-)-Pseudosemiglabrin: A Flavanone Isolated from the Aerial Parts of Tephrosia apollinea
LE Ahmed Hassan, MB Khadeer Ahamed… - PLoS …, 2014 - journals.plos.org
Tephrosia apollinea is a perennial shrublet widely distributed in Africa and is known to have
medicinal properties. The current study describes the bio-assay (cytotoxicity) guided …
medicinal properties. The current study describes the bio-assay (cytotoxicity) guided …
Novel Bis-spiro-labdane type Diterpenes from Leonotis nepetifolia: Isolation, Semi-synthesis, and Evaluation of their Cytotoxic Activities
Traditional medicinal plants offer huge opportunities to discover novel therapeutics against
many diseases. Investigation into the chemical diversity of the traditional medicinal plant …
many diseases. Investigation into the chemical diversity of the traditional medicinal plant …
Synthesis, characterization, and anticancer activity of new N, N′-Diarylthiourea derivative against breast cancer cells
The goal of the current study was to prepare two new homologous series of N, N′-
diarylurea and N, N′-diarylthiourea derivatives to investigate the therapeutic effects of …
diarylurea and N, N′-diarylthiourea derivatives to investigate the therapeutic effects of …
Potential anti-hepatocellular carcinoma properties and mechanisms of action of clerodane diterpenes isolated from Polyalthia longifolia seeds
VB Tatipamula, CV Thonangi, TC Dakal, GS Vedula… - Scientific Reports, 2022 - nature.com
Diterpenes are secondary metabolites that have attracted much attention due to their
potential biological activities including anti-cancer potential. The aim of the current study is …
potential biological activities including anti-cancer potential. The aim of the current study is …
Two new flavonoids and anticancer activity of Hymenosporum flavum: in vitro and molecular docking studies
RF Taher, AA Al-Karmalawy… - Journal of …, 2021 - herbmedpharmacol.com
Abstract Introduction: Hymenosporum flavum (Hook.) F. Muell. is the sole species within the
genus Hymenosporum is known for its antimicrobial activity. The current study aims to …
genus Hymenosporum is known for its antimicrobial activity. The current study aims to …
Chamaejasmenin E from Stellera chamaejasme induces apoptosis of hepatocellular carcinoma cells by targeting c-Met in vitro and in vivo
XQ Yu, QL Yan, S Shen, ZY Cheng, XX Huang… - Bioorganic …, 2022 - Elsevier
Hepatocellular carcinoma (HCC), the most prevalent liver cancer, is considered one of the
most lethal malignancies with a dismal outcome. There is an urgent need to find novel …
most lethal malignancies with a dismal outcome. There is an urgent need to find novel …
Anti-proliferative activity of Labdane Diterpenes isolated from Polyalthia cerasoides and their molecular interaction studies
RY Siddappa, SJ Aditya Rao, BM Usha… - Current Drug …, 2022 - ingentaconnect.com
Background: Polyalthia cerasoides is well known for its therapeutic effects and is extensively
used by the tribal people of South India and Africa to treat infertility, toothache, inflammation …
used by the tribal people of South India and Africa to treat infertility, toothache, inflammation …
Assessment of Cytotoxic/Antitumour Potential and in silico Study of Salazinic Acid Isolated from Parmotrema concurrens
MA da Conceição de Lira, MM da Silva… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Introduction: Despite numerous scientific advances, cancer continues to be one of the main
causes of death in the world. This situation has driven the search for promising molecules …
causes of death in the world. This situation has driven the search for promising molecules …