Atrial overexpression of microRNA-27b attenuates angiotensin II-induced atrial fibrosis and fibrillation by targeting ALK5

Y Wang, H Cai, H Li, Z Gao, K Song - Human Cell, 2018 - Springer
Atrial fibrosis influences atrial fibrillation (AF) development by transforming growth factor
beta 1 (TGF-β1)/Smad pathway. Although microRNAs are implicated in the pathogenesis of …

miR-29b ameliorates atrial fibrosis in rats with atrial fibrillation by targeting TGFβRΙ and inhibiting the activation of Smad-2/3 pathway

X Han, S Wang, Z Yong, X Zhang, X Wang - Journal of Bioenergetics and …, 2022 - Springer
Objective Atrial fibrillation (AF) is a major cause of stroke with lifetime risks. microRNAs
(miRNAs) are associated with AF attenuation, yet the mechanism remains unknown. This …

MiR-324-3p regulates fibroblast proliferation via targeting TGF-β1 in atrial fibrillation

J Xu, S Lei, S Sun, W Zhang, F Zhu, H Yang… - International Heart …, 2020 - jstage.jst.go.jp
Atrial fibrillation (AF), one of the common clinical arrhythmias, lacks effective treatment
manners. Cardiac fibroblasts play an essential role in myocardial fibrosis and cardiac …

Overexpression of MiR‐29b‐3p inhibits atrial remodeling in rats by targeting PDGF‐B signaling pathway

X Lv, P Lu, Y Hu, T Xu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
Purpose. Studies have found that microRNAs (miRNAs) are closely associated with atrial
fibrillation, but their specific mechanism remains unclear. The purpose of this experiment is …

MicroRNA-21 via dysregulation of WW domain-containing protein 1 regulate atrial fibrosis in atrial fibrillation

H Tao, M Zhang, JJ Yang, KH Shi - Heart, Lung and Circulation, 2018 - Elsevier
Background microRNAs (miRs) have been reported to regulate cell biological functions. To
explore the underlying mechanism of miR-21 involvement in patients with atrial fibrosis and …

Micro RNA‐30c suppresses the pro‐fibrogenic effects of cardiac fibroblasts induced by TGF‐β1 and prevents atrial fibrosis by targeting TGF β RII

J Xu, H Wu, S Chen, B Qi, G Zhou, L Cai… - Journal of Cellular …, 2018 - Wiley Online Library
Atrial fibrosis serves as an important contributor to atrial fibrillation (AF). Recent data have
suggested that micro RNA‐30c (miR‐30c) is involved in fibrotic remodelling and cancer …

MicroRNA‐146b‐5p promotes atrial fibrosis in atrial fibrillation by repressing TIMP4

Q Ye, Q Liu, X Ma, S Bai, P Chen… - Journal of Cellular …, 2021 - Wiley Online Library
Alteration of tissue inhibitors of matrix metalloproteinases (TIMP)/matrix metalloproteinases
(MMP) associated with collagen upregulation has an important role in sustained atrial …

[HTML][HTML] Relationship between circulating miRNA-21, atrial fibrosis, and atrial fibrillation in patients with atrial enlargement

H Chen, F Zhang, YL Zhang… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: Atrial fibrosis is a landmark of cardiac remodeling to perpetuate atrial fibrillation
(AF), and recent studies have indicated that microRNAs (miRNAs) are essential regulators of …

MicroRNA29: a mechanistic contributor and potential biomarker in atrial fibrillation

K Dawson, R Wakili, B Ördög, S Clauss, Y Chen… - Circulation, 2013 - Am Heart Assoc
Background—Congestive heart failure (CHF) causes atrial fibrotic remodeling, a substrate
for atrial fibrillation (AF) maintenance. MicroRNA29 (miR29) targets extracellular matrix …

Overexpression of miR‐27b‐3p Targeting Wnt3a Regulates the Signaling Pathway of Wnt/β‐Catenin and Attenuates Atrial Fibrosis in Rats with Atrial Fibrillation

X Lv, J Li, Y Hu, S Wang, C Yang, C Li… - … Medicine and Cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) are regarded as a potential method for the treatment of atrial
fibrillation (AF) although its molecular mechanism remains unknown. We found in our …