Pertussis vaccines containing reduced amounts of antigen have been considered primarily
for use in adolescents and adults to date. We evaluated a reduced antigen content …

High rates of pertussis disease in adolescents suggest that additional boosting against
pertussis would be beneficial. A combined acellular-pertussis-containing booster vaccine …

Background: The rising incidence of pertussis amongst adults and adolescents in
industrialised countries could be reduced by replacing tetanus and diphtheria (Td) boosters …

Reduced-antigen-content pertussis vaccines designed initially for booster vaccination of
adolescents and adults can also be used to vaccinate pre-school age children. Combination …

Pertussis continues to circulate in Chinese communities and older children, adolescents and
adults are sources of infection for unprotected infants. Two studies conducted in Jiangsu …

Vaccination against diphtheria, tetanus, and pertussis (DTP) has achieved great success in
infants and younger children in China. However, pertussis booster vaccination in older …

Many countries recommend diphtheria, tetanus and/or poliomyelitis boosters in adolescents
or adults and the need for pertussis booster vaccination beyond childhood is increasingly …

Background. Pertussis is increasingly recognized as an important cause of cough illness in
adolescents and adults. Purpose. To evaluate the safety and antibody response to a single …

A trial to compare the reactogenicity and immunogenicity of a reduced antigen content
diphtheria–tetanus–acellular pertussis (dTpa) vaccine with diphtheria–tetanus–whole-cell …

Background. The recent introduction of acellular pertussis vaccines (Pa) offers the possibility
of booster doses in older children and adults. This can be conveniently accomplished by …