Cytokinesis is crucial for integrating genome inheritance and cell functions. In multicellular
organisms, Rho-guanine nucleotide exchange factors (GEFs) and Rho GTPases are key …

Cytokinesis is the last step of the cell-division cycle, which requires precise spatial and
temporal regulation to ensure genetic stability. Rho guanine nucleotide exchange factors …

Division-site selection and contractile-ring assembly are two crucial steps in cytokinesis. In
fission yeast, the anillin-like Mid1 protein specifies the division site at the cell equator by …

Correct positioning of the cell division machinery is key to genome stability.
Schizosaccharomyces pombe is an attractive organism to study cytokinesis as it, like higher …

Correct positioning of the cell-division plane is crucial for cell function in all organisms. The
fission yeast Schizosaccharomyces pombe divides by utilizing an actomyosin-based …

Rho GTPases, activated by Rho guanine nucleotide exchange factors (GEFs), are
conserved molecular switches for signal transductions that regulate diverse cellular …

Correct positioning of the cell division machinery is crucial for genomic stability and cell fate
determination. The fission yeast Schizosaccharomyces pombe, like animal cells, divides …

Division site positioning is critical for both symmetric and asymmetric cell divisions. In many
organisms, positive and negative signals cooperate to position the contractile actin ring for …

Strategies to position the division apparatus exhibit a bewildering diversity [1], but how these
mechanisms evolve remains virtually unknown. Here, we explore the plasticity of division …

Spatial and timely coordination of cytokinesis is crucial for the maintenance of organelle
inheritance and genome integrity. The mitotic exit network (MEN) pathway controls both the …