Role of lysophosphatidylcholine (LPC) in atherosclerosis
T Matsumoto, T Kobayashi… - Current medicinal …, 2007 - ingentaconnect.com
Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid generated by
pathological activities. LPC is also a major phospholipid component of oxidized low-density …
pathological activities. LPC is also a major phospholipid component of oxidized low-density …
Metabolism and atherogenic disease association of lysophosphatidylcholine
G Schmitz, K Ruebsaamen - Atherosclerosis, 2010 - Elsevier
Lysophosphatidylcholine (LPC) is a major plasma lipid that has been recognized as an
important cell signalling molecule produced under physiological conditions by the action of …
important cell signalling molecule produced under physiological conditions by the action of …
An updated review of pro-and anti-inflammatory properties of plasma lysophosphatidylcholines in the vascular system
E Knuplez, G Marsche - International Journal of Molecular Sciences, 2020 - mdpi.com
Lysophosphatidylcholines are a group of bioactive lipids heavily investigated in the context
of inflammation and atherosclerosis development. While present in plasma during …
of inflammation and atherosclerosis development. While present in plasma during …
Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells
N Aiyar, J Disa, Z Ao, H Ju, S Nerurkar… - Molecular and cellular …, 2007 - Springer
Lysophosphatidylcholine (LPC) is the major bioactive lipid component of oxidized LDL,
thought to be responsible for many of the inflammatory effects of oxidized LDL described in …
thought to be responsible for many of the inflammatory effects of oxidized LDL described in …
Nanomolar concentrations of lysophosphatidylcholine recruit monocytes and induce pro-inflammatory cytokine production in macrophages
KE Olofsson, L Andersson, J Nilsson… - … and biophysical research …, 2008 - Elsevier
Lysophosphatidylcholine (LPC) has been attributed a pro-inflammatory role in
atherosclerosis. Cell culture studies have identified stimulation of cytokine expression and …
atherosclerosis. Cell culture studies have identified stimulation of cytokine expression and …
The mechanisms of lysophosphatidylcholine in the development of diseases
Lysophosphatidylcholine (LPC) is the main component of oxidatively damaged low-density
lipoprotein (oxLDL). LPC originates from the cleavage of phosphatidylcholine by …
lipoprotein (oxLDL). LPC originates from the cleavage of phosphatidylcholine by …
Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium
Z Zhou, P Subramanian, G Sevilmis, B Globke… - Cell metabolism, 2011 - cell.com
Oxidatively modified low-density lipoprotein (oxLDL) plays a key role in the initiation of
atherosclerosis by increasing monocyte adhesion. The mechanism that is responsible for …
atherosclerosis by increasing monocyte adhesion. The mechanism that is responsible for …
Lysophosphatidic acid and its receptors: pharmacology and therapeutic potential in atherosclerosis and vascular disease
Lysophosphatidic acid (LPA) is a collective name for a set of bioactive lipid species. Via six
widely distributed G protein-coupled receptors (GPCRs), LPA elicits a plethora of biological …
widely distributed G protein-coupled receptors (GPCRs), LPA elicits a plethora of biological …
Lysophosphatidic acid in atherosclerotic diseases
A Schober, W Siess - British journal of pharmacology, 2012 - Wiley Online Library
Lysophosphatidic acid (LPA) is a potent bioactive phospholipid. As many other biological
active lipids, LPA is an autacoid: it is formed locally on demand, and it acts locally near its …
active lipids, LPA is an autacoid: it is formed locally on demand, and it acts locally near its …
Lysophosphatidylcholine and secretory phospholipase A2 in vascular disease: mediators of endothelial dysfunction and atherosclerosis.
P Kougias, H Chai, PH Lin, AB Lumsden… - … medical journal of …, 2005 - europepmc.org
Lysophosphatidylcholine (LPC) is the major component of oxidized low density lipoprotein
(oxLDL) and it has the ability to initiate or amplify several steps in atherogenesis due to its …
(oxLDL) and it has the ability to initiate or amplify several steps in atherogenesis due to its …