IL‐17 and IL‐22 in immunity: Driving protection and pathology
K Eyerich, V Dimartino, A Cavani - European journal of …, 2017 - Wiley Online Library
IL‐17 and IL‐22 are tissue‐signaling cytokines that favor protection and regeneration of
barrier organs such as the skin, lung, and gastrointestinal system. Both cytokines share …
barrier organs such as the skin, lung, and gastrointestinal system. Both cytokines share …
IL-17 in the pathogenesis of disease: good intentions gone awry
S Majumder, MJ McGeachy - Annual review of immunology, 2021 - annualreviews.org
The IL-17 family is an evolutionarily old cytokine family consisting of six members (IL-17A
through IL-17F). IL-17 family cytokines signal through heterodimeric receptors that include …
through IL-17F). IL-17 family cytokines signal through heterodimeric receptors that include …
The IL-17 family of cytokines in health and disease
The interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines, IL-17A
through IL-17F. IL-17A, the prototypical member of this family, just passed the 25 th …
through IL-17F. IL-17A, the prototypical member of this family, just passed the 25 th …
IL-17 and IL-22: siblings, not twins
S Eyerich, K Eyerich, A Cavani, C Schmidt-Weber - Trends in immunology, 2010 - cell.com
T helper (Th) cell subsets secrete cytokines that regulate other immune cells. Interleukin (IL)-
17 and IL-22 belong to a new class of cytokines with predominant effects on epithelial cells …
17 and IL-22 belong to a new class of cytokines with predominant effects on epithelial cells …
The IL-17 family in diseases: from bench to bedside
L Huangfu, R Li, Y Huang, S Wang - Signal Transduction and Targeted …, 2023 - nature.com
Abstract The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and
recently, all of its related receptors have been discovered. IL-17 was first discovered …
recently, all of its related receptors have been discovered. IL-17 was first discovered …
IL-17 signaling: the yin and the yang
Interleukin (IL)-17 is the founding member of a novel family of inflammatory cytokines. While
the proinflammatory properties of IL-17 are key to its host-protective capacity, unrestrained IL …
the proinflammatory properties of IL-17 are key to its host-protective capacity, unrestrained IL …
IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases
X Song, Y Qian - Cellular signalling, 2013 - Elsevier
Inflammation is the immediate protective response of the body to pathogen invasions,
allergen challenges, chemical exposures or physical injuries. Acute inflammation usually …
allergen challenges, chemical exposures or physical injuries. Acute inflammation usually …
IL-17 signaling in host defense and inflammatory diseases
Y Qian, Z Kang, C Liu, X Li - Cellular & molecular immunology, 2010 - nature.com
Abstract Interleukin (IL)-17, the signature cytokine secreted by T helper (Th) 17 cells, plays
important roles in host defense against extracellular bacterial infection and fungal infection …
important roles in host defense against extracellular bacterial infection and fungal infection …
Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons?
H Mühl - Frontiers in immunology, 2013 - frontiersin.org
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share
characteristic properties such as defined structural features, usage of IL-10R2 as one …
characteristic properties such as defined structural features, usage of IL-10R2 as one …
IL‐22, not simply a Th17 cytokine
Summary Interleukin‐22 (IL‐22) has important functions in host defense at mucosal surfaces
as well as in tissue repair. It is unique as a cytokine that is produced by immune cells …
as well as in tissue repair. It is unique as a cytokine that is produced by immune cells …