Comprehensive research on past and future therapeutic strategies devoted to treatment of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a rapidly debilitating fatal neurodegenerative disorder,
causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS …
causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS …
Potential therapeutic drugs and methods for the treatment of amyotrophic lateral sclerosis
G Yacila, Y Sari - Current medicinal chemistry, 2014 - ingentaconnect.com
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder caused by damage of
motoneurons leading to paralysis state and long term disability. Riluzole is currently the only …
motoneurons leading to paralysis state and long term disability. Riluzole is currently the only …
Novel therapeutic targets for amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is an untreatable and fatal neurodegenerative disease
that is identified by the loss of motor neurons in the spinal cord, brain stem, and motor cortex …
that is identified by the loss of motor neurons in the spinal cord, brain stem, and motor cortex …
The panoramic view of amyotrophic lateral sclerosis: A fatal intricate neurological disorder
S Dhasmana, A Dhasmana, AS Narula, M Jaggi… - Life Sciences, 2022 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disease affecting
both upper and lower motor neurons. In the United States alone, there are 16,000–20,000 …
both upper and lower motor neurons. In the United States alone, there are 16,000–20,000 …
A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?
X Xu, D Shen, Y Gao, Q Zhou, Y Ni, H Meng… - Translational …, 2021 - Springer
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease involving
both upper and lower motor neurons, leading to paralysis and eventually death …
both upper and lower motor neurons, leading to paralysis and eventually death …
Therapeutic neuroprotective agents for amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal chronic neurodegenerative disease whose
hallmark is proteinaceous, ubiquitinated, cytoplasmic inclusions in motor neurons and …
hallmark is proteinaceous, ubiquitinated, cytoplasmic inclusions in motor neurons and …
Diagnosis, pathogenesis and therapeutic targets in amyotrophic lateral sclerosis
J Costa, C Gomes… - CNS & Neurological …, 2010 - ingentaconnect.com
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease of the motor
system. The diagnosis is clinical, but additional investigations such as electromyography …
system. The diagnosis is clinical, but additional investigations such as electromyography …
New developments and opportunities in drugs being trialed for amyotrophic lateral sclerosis from 2020 to 2022
JS Jiang, Y Wang, M Deng - Frontiers in pharmacology, 2022 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that
primarily affects motor neurons in the brain and spinal cord. In the recent past, there have …
primarily affects motor neurons in the brain and spinal cord. In the recent past, there have …
Shortcomings in the current amyotrophic lateral sclerosis trials and potential solutions for improvement
N Katyal, R Govindarajan - Frontiers in neurology, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a clinically progressive neurodegenerative syndrome
predominantly affecting motor neurons and their associated tracts. Riluzole and edaravone …
predominantly affecting motor neurons and their associated tracts. Riluzole and edaravone …
Current view and perspectives in amyotrophic lateral sclerosis
S Mathis, P Couratier, A Julian, P Corcia… - Neural Regeneration …, 2017 - journals.lww.com
Amyotrophic lateral sclerosis (ALS), identified as a distinct clinical entity by Charcot since the
end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that …
end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that …