Traditional genetic counseling has focused on the target gene and its natural progress with
respect to disease risk. Next-generation sequencing (NGS) can produce information on …

Next generation sequencing (NGS) is dramatically increasing the number of clinically
available genetic tests and thus the number of patients in which such testing may be …

Advances in next‐generation sequencing (NGS) and rapid reductions in cost have
increased the use of such technologies in research and clinical practice. However, many …

Purpose: Clinical next-generation sequencing (CNGS) is introducing new opportunities and
challenges into the practice of medicine. Simultaneously, these technologies are generating …

Genome-wide sequencing (GWS) is the most sensitive test available for detecting
pathogenic genetic variants. In line with guidelines in North America and Europe, best …

Desai AN, Jere A. Next‐generation sequencing: ready for the clinics? Next‐generation
sequencing (NGS) has transformed genomic research by decreasing the cost of sequencing …

Clinical Genomics provides an overview of the various next-generation sequencing (NGS)
technologies that are currently used in clinical diagnostic laboratories. It presents key …

With the introduction of Next Generation Sequencing (NGS) techniques increasing numbers
of disease-associated variants are being identified. This ongoing progress might lead to …

Next-generation sequencing (NGS) techniques have greatly accelerated the molecular
elucidation of Mendelian disorders, and affordable NGS-based diagnostic tests are around …

We are entering an era in which the cost of clinical whole-genome and targeted sequencing
tests is no longer prohibitive to their application. However, currently the infrastructure is not …