Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects
upper motor neurons (MNs) comprising the corticospinal tract and lower MNs arising from …

Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous disorder characterized by
loss of motor neurons, resulting in paralysis and death. Multiple mechanisms of motor …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with
selective loss of upper and lower motor neurons. At sites of motor neuron injury …

Neurodegenerative disorders are characterized by the selective vulnerability and
progressive loss of discrete neuronal populations. Non-neuronal cells appear to significantly …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
muscle weakness due to the degeneration of the upper and lower motor neurons …

Amyotrophic lateral sclerosis (ALS), a devastating motor neuron disease involving complex
genetic and environmental factors, is associated with neuroinflammation. Preclinical and …

Amyotrophic lateral sclerosis (ALS) is a debilitating and rapidly fatal neurodegenerative
disease. Despite decades of research and many new insights into disease biology over the …

Increasing evidence suggests that the pathogenesis of neurodegenerative diseases
including amyotrophic lateral sclerosis (ALS) is not restricted to the neurons but attributed to …

Neurological dysfunction and motor neuron degeneration in amyotrophic lateral sclerosis
(ALS) is strongly associated with neuroinflammation reflected by activated microglia and …

Neuroinflammation is one of the main hallmarks of amyotrophic lateral sclerosis (ALS).
Recently, peripheral immune cells were discovered as pivotal players that promptly …