Principles and applications of sono-optogenetics

F Yang, SJ Kim, X Wu, H Cui, SK Hahn… - Advanced drug delivery …, 2023 - Elsevier
Optogenetics has revolutionized neuroscience research through its spatiotemporally precise
activation of specific neurons by illuminating light on opsin-expressing neurons. A long …

Ultrasound-Induced Cascade Amplification in a Mechanoluminescent Nanotransducer for Enhanced Sono-Optogenetic Deep Brain Stimulation

W Wang, KW Kevin Tang, I Pyatnitskiy, X Liu, X Shi… - ACS …, 2023 - ACS Publications
Remote and genetically targeted neuromodulation in the deep brain is important for
understanding and treatment of neurological diseases. Ultrasound-triggered …

Activation of mechanoluminescent nanotransducers by focused ultrasound enables light delivery to deep-seated tissue in vivo

S Jiang, X Wu, F Yang, NJ Rommelfanger, G Hong - Nature Protocols, 2023 - nature.com
Light is used extensively in biological and medical research for optogenetic
neuromodulation, fluorescence imaging, photoactivatable gene editing and light-based …

Ultrasound-triggered in situ photon emission for noninvasive optogenetics

W Wang, X Wu, KW Kevin Tang… - Journal of the …, 2023 - ACS Publications
Optogenetics has revolutionized neuroscience understanding by allowing spatiotemporal
control over cell-type specific neurons in neural circuits. However, the sluggish development …

Sono-optogenetics facilitated by a circulation-delivered rechargeable light source for minimally invasive optogenetics

X Wu, X Zhu, P Chong, J Liu… - Proceedings of the …, 2019 - National Acad Sciences
Optogenetics, which uses visible light to control the cells genetically modified with light-
gated ion channels, is a powerful tool for precise deconstruction of neural circuitry with …

Ultrasound triggered organic mechanoluminescence materials

W Wang, A Tasset, I Pyatnitskiy, HG Mohamed… - Advanced drug delivery …, 2022 - Elsevier
Ultrasound induced organic mechanoluminescence materials have become one of the focal
topics in wireless light sources since they exhibit high spatiotemporal resolution …

Sonogenetics for Monitoring and Modulating Biomolecular Function by Ultrasound

J Hahmann, A Ishaqat, T Lammers… - Angewandte Chemie …, 2024 - Wiley Online Library
Ultrasound technology, synergistically harnessed with genetic engineering and chemistry
concepts, has started to open the gateway to the remarkable realm of sonogenetics—a …

[HTML][HTML] X-optogenetics and U-optogenetics: feasibility and possibilities

R Berry, M Getzin, L Gjesteby, G Wang - Photonics, 2015 - mdpi.com
Optogenetics is an established technique that uses visible light to modulate membrane
voltage in neural cells. Although optogenetics allows researchers to study parts of the brain …

[HTML][HTML] Non-invasive optogenetics with ultrasound-mediated gene delivery and red-light excitation

AN Pouliopoulos, MF Murillo, RL Noel, AJ Batts, R Ji… - Brain stimulation, 2022 - Elsevier
Optogenetics has revolutionized the capability of controlling genetically modified neurons in
vitro and in vivo and has become an indispensable neuroscience tool. Using light as a …

[HTML][HTML] Ultrasound modulates ion channel currents

J Kubanek, J Shi, J Marsh, D Chen, C Deng, J Cui - Scientific reports, 2016 - nature.com
Transcranial focused ultrasound (US) has been demonstrated to stimulate neurons in
animals and humans, but the mechanism of this effect is unknown. It has been hypothesized …