HIV-1 Drug Resistance Detected by Next-Generation Sequencing among ART-Naïve Individuals: A Systematic Review and Meta-Analysis
F Ouyang, D Yuan, W Zhai, S Liu, Y Zhou, H Yang - Viruses, 2024 - mdpi.com
Background: There are an increasing number of articles focused on the prevalence and
clinical impact of pretreatment HIV drug resistance (PDR) detected by Sanger sequencing …
clinical impact of pretreatment HIV drug resistance (PDR) detected by Sanger sequencing …
Low-abundance drug-resistant HIV-1 variants in antiretroviral drug-naive individuals: a systematic review of detection methods, prevalence, and clinical impact
Background The presence of high-abundance drug-resistant HIV-1 jeopardizes success of
antiretroviral therapy (ART). Despite numerous investigations, the clinical impact of low …
antiretroviral therapy (ART). Despite numerous investigations, the clinical impact of low …
Applying Next-Generation Sequencing to Track HIV-1 Drug Resistance Mutations Circulating in Portugal
Background: The global scale-up of antiretroviral treatment (ART) offers significant health
benefits by suppressing HIV-1 replication and increasing CD4 cell counts. However …
benefits by suppressing HIV-1 replication and increasing CD4 cell counts. However …
Prevalence of HIV-1 pre-treatment drug resistance in a southern province of Iran, 2016-2017
A Memarnejadian, H Gouklani, S Mohammadi… - Archives of …, 2018 - Springer
HIV-1 transmitted drug resistance (TDR) occurs when primary viruses bear drug resistance
mutations (DRMs). TDR causes first-line antiretroviral (ARV) therapy (ART) failure and is …
mutations (DRMs). TDR causes first-line antiretroviral (ARV) therapy (ART) failure and is …
Prevalence of HIV-1 drug resistance mutations in proviral DNA in the Swiss HIV Cohort Study, a retrospective study from 1995 to 2018
B Jaha, CD Schenkel, L Jörimann… - Journal of …, 2023 - academic.oup.com
Background Genotypic resistance testing (GRT) is routinely performed upon diagnosis of
HIV-1 infection or during virological failure using plasma viral RNA. An alternative source for …
HIV-1 infection or during virological failure using plasma viral RNA. An alternative source for …
Transmitted HIV‐1 drug resistance in a large international cohort using next‐generation sequencing: results from the Strategic Timing of Antiretroviral Treatment …
JD Baxter, D Dunn, A Tostevin, RL Marvig… - HIV …, 2021 - Wiley Online Library
Objectives The aim of this analysis was to characterize transmitted drug resistance (TDR) in
Strategic Timing of Antiretroviral Treatment (START) study participants by next‐generation …
Strategic Timing of Antiretroviral Treatment (START) study participants by next‐generation …
HIV drug resistance mutations (DRMs) detected by deep sequencing in virologic failure subjects on therapy from Hunan Province, China
Objective Determine HIV drug resistance mutations (DRMs) prevalence at low and high
levels in ART-experienced patients experiencing virologic failure (VF). Methods 29 subjects …
levels in ART-experienced patients experiencing virologic failure (VF). Methods 29 subjects …
Prevalence of transmitted HIV drug resistance in antiretroviral treatment naïve newly diagnosed individuals in China
S Zhao, Y Feng, J Hu, Y Li, Z Zuo, J Yan, J Zhang… - Scientific Reports, 2018 - nature.com
To investigate the prevalence and temporal trend of transmitted drug resistance (TDR), a
nationwide cross-sectional survey was conducted among 5627 ART naïve newly diagnosed …
nationwide cross-sectional survey was conducted among 5627 ART naïve newly diagnosed …
Transmitted drug resistance in antiretroviral therapy-naive persons with acute/early/primary HIV infection: a systematic review and meta-analysis
C Guo, Y Wu, Y Zhang, X Liu, A Li, M Gao… - Frontiers in …, 2021 - frontiersin.org
Background: The widespread use of antiretroviral therapy (ART) has raised concerns about
the emergence of HIV transmitted drug resistance (TDR). Acute HIV infection (AHI) was the …
the emergence of HIV transmitted drug resistance (TDR). Acute HIV infection (AHI) was the …
HIV-1 drug resistance genotyping in resource limited settings: current and future perspectives in sequencing technologies
Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …