[HTML][HTML] Structures and target RNA preferences of the RNA-binding protein family of IGF2BPs: An overview
SM Korn, CJ Ulshöfer, T Schneider, A Schlundt - Structure, 2021 - cell.com
Insulin-like growth factor 2 mRNA-binding proteins (IMPs, IGF2BPs) act in mRNA transport
and translational control but are oncofetal tumor marker proteins. The IMP protein family …
and translational control but are oncofetal tumor marker proteins. The IMP protein family …
Structural basis of IMP3 RRM12 recognition of RNA
The IMP family of RNA binding proteins, also named as insulin-like growth factor 2 (IGF2)
mRNA-binding proteins (IGF2BPs), are highly conserved RNA regulators that are involved in …
mRNA-binding proteins (IGF2BPs), are highly conserved RNA regulators that are involved in …
IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties
Abstract IGF2 mRNA-binding protein 1 (IMP1) is a key regulator of messenger RNA (mRNA)
metabolism and transport in organismal development and, in cancer, its mis-regulation is an …
metabolism and transport in organismal development and, in cancer, its mis-regulation is an …
[HTML][HTML] The structural basis for RNA selectivity by the IMP family of RNA-binding proteins
The IGF2 mRNA-binding proteins (ZBP1/IMP1, IMP2, IMP3) are highly conserved post-
transcriptional regulators of RNA stability, localization and translation. They play important …
transcriptional regulators of RNA stability, localization and translation. They play important …
IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer
N Degrauwe, ML Suvà, M Janiszewska… - Genes & …, 2016 - genesdev.cshlp.org
IMPs, also known as insulin-like growth factor 2 (IGF2) messenger RNA (mRNA)-binding
proteins (IGF2BPs), are highly conserved oncofetal RNA-binding proteins (RBPs) that …
proteins (IGF2BPs), are highly conserved oncofetal RNA-binding proteins (RBPs) that …
The roles of insulin‐like growth factor 2 mRNA‐binding protein 2 in cancer and cancer stem cells
J Cao, Q Mu, H Huang - Stem cells international, 2018 - Wiley Online Library
RNA‐binding proteins (RBPs) mediate the localization, stability, and translation of the target
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …
[HTML][HTML] Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
T Schneider, LH Hung, M Aziz, A Wilmen… - Nature …, 2019 - nature.com
How multidomain RNA-binding proteins recognize their specific target sequences, based on
a combinatorial code, represents a fundamental unsolved question and has not been …
a combinatorial code, represents a fundamental unsolved question and has not been …
A family of IGF-II mRNA binding proteins (IMP) involved in RNA trafficking
F C. Nielsen, Jacob Nielsen, Jan … - Scandinavian journal of …, 2001 - Taylor & Francis
During a search for trans-acting factors associating with insulin-like growth factor II (IGF-II)
mRNAs, we recently identified a family of three I GF-II m RNA-binding P roteins (IMP1, IMP2 …
mRNAs, we recently identified a family of three I GF-II m RNA-binding P roteins (IMP1, IMP2 …
The biological function of IGF2BPs and their role in tumorigenesis
QY Du, ZM Zhu, DS Pei - Investigational new drugs, 2021 - Springer
The insulin-like growth factor-2 mRNA-binding proteins (IGF2BPs) pertain to a highly
conservative RNA-binding family that works as a post-transcriptional fine-tuner for target …
conservative RNA-binding family that works as a post-transcriptional fine-tuner for target …
Nuclear transit of human zipcode-binding protein IMP1
J Nielsen, SK Adolph, E Rajpert-De Meyts… - Biochemical …, 2003 - portlandpress.com
The human IMPs (insulin-like growth factor II mRNA-binding proteins) belong to a vertebrate
zipcode-binding protein family consisting of two RNA recognition motifs and four K …
zipcode-binding protein family consisting of two RNA recognition motifs and four K …