The hepatoprotective properties of silibinin, as well its therapeutic potential as an anticancer
and chemo-preventive agent, have failed to progress towards clinical development and …

Since cancer is a multifactorial disease with a high mortality rate, the study of new
therapeutic strategies is one of the main objectives in modern research. Numerous …

The tremendous therapeutic potential of curcumin as a chemopreventive, antineoplastic and
chemosensitizing agent has failed to progress towards clinical development and …

In drug development field, active substance solubilization is among most important factors.
Expanding significance is set on the role of drug solubilization process. The formation of a …

An inorganic–organic hybrid material, MCM-allylCalix, was synthesized by covalent
modification of an MCM-41 surface with a tetra-allyl calixarene conjugate. The synthesized …

Selective internalization in cancer cells has great potential to reduce the side effects of
cancer therapy. One effective approach to increase targeting to cancer cells is modification …

Objectives This paper describes the development and optimization of a nanoparticle
delivery platform for the anticancer agent, paclitaxel, using a novel amphiphilic carrier …

The importance of calixarene nanobaskets in drug development and controlling their toxicity
comes back to their ability to encapsulate the drug species and biological compounds. New …

In this paper, the spontaneous formation of nanoparticles through supramolecular
interactions between chitosan and sulfonated calix [4] resorcinarenes was demonstrated. A …

Nano-drug delivery systems (nanoDDS) have been extensively investigated clinically to
improve the therapeutic effect of anti-cancer drugs. However, the complicated synthesis …