Background Lipopolysaccharide (LPS) is an endotoxin that leads to inflammation in many
organs, including liver. It binds to pattern recognition receptors, that generally recognise …

Endotoxin tolerance (ET) is an important phenomenon, which affects inflammation and
phagocytosis. Pretreatment with low dose of lipopolysaccharide (LPS) can protect liver injury …

Sepsis caused by infection is one of the most important problems of clinical medicine. This
study aimed to determine the effect of Apilarnil (API), a bee product, on lipopolysaccharide …

Lipopolysaccharide (LPS), a well-conserved cell wall component of Gram positive bacteria,
exerts its toxic effects via inducing oxidative and pro-inflammatory responses. Red palm oil …

Septic acute liver injury is one of the leading causes of fatalities in patients with sepsis. Toll-
like receptor 4 (TLR4) plays a vital role in response to lipopolysaccharide (LPS) challenge …

Thymol is a natural antibacterial agent found in the essential oil extracted from thyme, which
has been proven to be beneficial in food and medicine. Meanwhile, the NOD-like receptor …

Aims: Emodin is an anthraquinone with potential anti-inflammatory properties. However, the
possible molecular mechanisms and protective effects of emodin are not clear. The objective …

Abstract Background and Aim Hepatic cirrhosis is the final stage of liver dysfunction,
characterized by diffuse fibrosis, which is the main response to the liver injury. This study is …

OBJECTIVE: Drug-induced liver injury has become a serious public health problem that
cannot be ignored. Although the mechanism of acetaminophen (APAP)-induced liver injury …

Abstract Lipopolysaccharide/d-Galactosamine (LPS/d-Gal)-induced acute liver injury is
characterized by significant inflammatory responses including TNF-α and interleukin-6 (IL-6) …