Background Diabetic nephropathy is one of the common complications of diabetes mellitus,
which seriously affects the life quality and health of patients. In this study, we aimed to …

Abstract Aims Catalpol (Cat) can ameliorate oxide stress and inflammation caused by
diabetic nephropathy (DN), but the molecular mechanisms are unclear. This study was …

Geniposide (GE) can effectively inhibit diabetic nephropathy (DN), but its mechanism is
unclear. The objective of this study was to explore the antidiabetic nephropathy effects of GE …

Dendrobium mixture (DMix) is a Traditional Chinese Medicine widely used for preventing
and treating diabetic nephropathy (DN). Autophagy contributes to DN development and …

Background Diabetic nephropathy (DN) is one of the main causes of end-stage renal
disease with scantly effective treatment. Numerous evidences indicated that macrophages …

Oxidative stress plays a crucial role in the progression of diabetic nephropathy in
hyperglycemic conditions. It has already been reported that mangiferin, a natural C-glucosyl …

This study investigated if the nephroprotective effect of Curcumin in streptozotocin-induced
type 1 diabetes mellitus (DM) in rats involves downregulation/inhibition of p 66 Shc and …

Type II diabetes-induced ischemic injuries are known to lead to the rapid degeneration of
the kidneys as a result of chronic renal failure. Chronic renal failure is a condition, which …

Background Type 2 diabetes (T2D) is aglobal health burden that accounts for about 90% of
all cases of diabetes. Injury to the kidneys is aserious complication of type 2 diabetes …

Objective To investigate the effect of baicalin on diabetic nephropathy (DN) rats and
podocytes and its mechanism. Methods The rat models with DN were established by high-fat …