Long-term follow-up and outcomes of retreatment in an expanded 50-patient single-center phase II prospective trial of 177Lu-PSMA-617 theranostics in metastatic …

J Violet, S Sandhu, A Iravani… - Journal of Nuclear …, 2020 - Soc Nuclear Med
177Lu-PSMA-617 is a radioligand with high affinity for prostate-specific membrane antigen
(PSMA), enabling targeted β-irradiation of prostate cancer. We have previously reported …

PSMA-targeted radionuclide therapy of metastatic castration-resistant prostate cancer with 177Lu-labeled PSMA-617

C Kratochwil, FL Giesel, M Stefanova… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is an excellent target for radionuclide therapy
of metastasized castration-resistant prostate cancer (mCRPC). Besides high affinity and long …

Third-line treatment and 177Lu-PSMA radioligand therapy of metastatic castration-resistant prostate cancer: a systematic review

FE von Eyben, G Roviello, T Kiljunen… - European journal of …, 2018 - Springer
Aims There is a controversy as to the relative efficacy of 177 Lu prostate specific membrane
antigen (PSMA) radioligand therapy (RLT) and third-line treatment for patients with …

German multicenter study investigating 177Lu-PSMA-617 radioligand therapy in advanced prostate cancer patients

K Rahbar, H Ahmadzadehfar… - Journal of Nuclear …, 2017 - Soc Nuclear Med
177Lu-labeled PSMA-617 is a promising new therapeutic agent for radioligand therapy
(RLT) of patients with metastatic castration-resistant prostate cancer (mCRPC). Initiated by …

177 Lu-PSMA-617 radioligand therapy of metastatic castration-resistant prostate cancer: Initial 254-patient results from a prospective registry (REALITY Study)

F Khreish, Z Ghazal, RJ Marlowe, F Rosar… - European Journal of …, 2022 - Springer
Purpose Preliminary data from retrospective analyses and recent data from large
randomized controlled trials suggest safety and efficacy of radioligand therapy (RLT) …

Lutetium-177–PSMA-617 for metastatic castration-resistant prostate cancer

O Sartor, J De Bono, KN Chi, K Fizazi… - … England Journal of …, 2021 - Mass Medical Soc
Background Metastatic castration-resistant prostate cancer remains fatal despite recent
advances. Prostate-specific membrane antigen (PSMA) is highly expressed in metastatic …

Clinical outcomes of 177Lu-PSMA radioligand therapy in earlier and later phases of metastatic castration-resistant prostate cancer grouped by previous taxane …

TW Barber, A Singh, HR Kulkarni… - Journal of Nuclear …, 2019 - Soc Nuclear Med
177Lu-labeled prostate-specific membrane antigen (PSMA) radioligand therapy using
PSMA-617 and PSMA-I&T ligands (177Lu-PRLT) is an emerging treatment in metastatic …

[177Lu]-PSMA-617 radionuclide treatment in patients with metastatic castration-resistant prostate cancer (LuPSMA trial): a single-centre, single-arm, phase 2 study

MS Hofman, J Violet, RJ Hicks, J Ferdinandus… - The Lancet …, 2018 - thelancet.com
Background Progressive metastatic castration-resistant prostate cancer is a highly lethal
disorder and new effective therapeutic agents that improve patient outcomes are urgently …

Radioligand therapy with 177Lu-PSMA-617 as a novel therapeutic option in patients with metastatic castration resistant prostate cancer

K Rahbar, A Bode, M Weckesser… - Clinical nuclear …, 2016 - journals.lww.com
Background Despite progress in treatment of metastatic castration-resistant prostate cancer
(mCRPC), new approaches are urgently needed. Recently theranostic concepts using …

[HTML][HTML] Preliminary experience with dosimetry, response and patient reported outcome after 177Lu-PSMA-617 therapy for metastatic castration-resistant prostate …

WP Fendler, S Reinhardt, H Ilhan, A Delker, G Böning… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Prostate cancer can be targeted by ligands to the prostate-specific membrane antigen
(PSMA). We aimed to evaluate dosimetry, safety and efficacy of 177 Lu-PSMA-617 …