Many pathological changes in solid tumours are caused by the accumulation of genetic
mutations and epigenetic molecular alterations. In addition, tumour progression is …

Bladder cancer (BC) constitutes one of the most diagnosed types of cancer worldwide.
Advancements in and new methodologies for DNA sequencing, leading to high-throughput …

Bladder cancer has been well known as immunotherapy-responsive disease as intravesical
therapy with BCG has been the standard of care for non-muscle invasive disease for several …

The microbiome is a new center of attention for studies on the pathogenesis of human
disease by focusing on the alterations of all microorganisms living in a particular site or …

Evidence suggests that microbiota may contribute to the pathogenesis of several diseases,
including cancer. In the case of bladder cancer, preliminary studies have found alterations in …

Recent investigation has proven that the bladder is not sterile. However, the implications of
this finding in the pathophysiology and management of urothelial cell carcinoma have not …

Bladder cancer is the 10th most common cancer worldwide. Approximately 75% of patients
with bladder cancer will present with non-muscle invasive disease. Patients are usually …

Introduction The presence of a microbiome in the urinary system has been established
through recent advancements in technology and investigation of microbial communities in …

Simple Summary The abundance of microbial species residing within tumors is correlated to
cancer progression across many different cancers, including bladder cancer. However, links …

Mounting evidence indicates that microbiome plays an important role in the development
and progression of cancer. The dogma that urine in healthy individuals must be sterile has …