Cancer‐associated fibroblasts in breast cancer: Challenges and opportunities
D Hu, Z Li, B Zheng, X Lin, Y Pan, P Gong… - Cancer …, 2022 - Wiley Online Library
The tumor microenvironment is proposed to contribute substantially to the progression of
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …
Cancer associated fibroblasts: role in breast cancer and potential as therapeutic targets
ABSTRACT Introduction: Cancer associated fibroblasts (CAFs) are the largest population of
stromal cells in breast tumors. Emerging evidence has suggested that CAFs are important …
stromal cells in breast tumors. Emerging evidence has suggested that CAFs are important …
Cancer-associated fibroblasts: a multifaceted driver of breast cancer progression
H Luo, G Tu, Z Liu, M Liu - Cancer letters, 2015 - Elsevier
Cancerous tissue is a complex mix of tumor cells, stromal cells and extracellular matrix
(ECM), all of which make up a disordered and aggressive niche in comparison with …
(ECM), all of which make up a disordered and aggressive niche in comparison with …
[HTML][HTML] Cancer-associated fibroblasts in breast cancer treatment response and metastasis
P Fernández-Nogueira, G Fuster, Á Gutierrez-Uzquiza… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is a major public health problem with a large impact on the
life of patients and their families. It is a highly curable disease when detected early, and an …
life of patients and their families. It is a highly curable disease when detected early, and an …
Cancer-associated fibroblasts as key regulators of the breast cancer tumor microenvironment
JM Houthuijzen, J Jonkers - Cancer and Metastasis Reviews, 2018 - Springer
Tumor cells exist in close proximity with non-malignant cells. Extensive and multilayered
crosstalk between tumor cells and stromal cells tailors the tumor microenvironment (TME) to …
crosstalk between tumor cells and stromal cells tailors the tumor microenvironment (TME) to …
[HTML][HTML] Cancer-associated fibroblasts: the chief architect in the tumor microenvironment
Stromal heterogeneity of tumor microenvironment (TME) plays a crucial role in malignancy
and therapeutic resistance. Cancer-associated fibroblasts (CAFs) are one of the major …
and therapeutic resistance. Cancer-associated fibroblasts (CAFs) are one of the major …
Breast cancer-associated fibroblasts: their roles in tumor initiation, progression and clinical applications
A Qiao, F Gu, X Guo, X Zhang, L Fu - Frontiers of Medicine, 2016 - Springer
Breast cancer is the most common malignant tumor in women, and the incidence of this
disease has increased in recent years because of changes in diet, living environment …
disease has increased in recent years because of changes in diet, living environment …
Cancer associated fibroblasts as novel promising therapeutic targets in breast cancer
S Salimifard, A Masjedi, M Hojjat-Farsangi… - … -Research and Practice, 2020 - Elsevier
Breast cancer is one of the most important women-related malignancies, which is incurable
(particularly in advanced stages) and tumor microenvironment is a number one accused part …
(particularly in advanced stages) and tumor microenvironment is a number one accused part …
[HTML][HTML] Cancer-associated fibroblasts: epigenetic regulation and therapeutic intervention in breast cancer
Simple Summary Drug resistance and insensitivity to treatments are the main challenges in
breast cancer therapy. Cancer-associated fibroblasts (CAFs) are heterogeneous stromal …
breast cancer therapy. Cancer-associated fibroblasts (CAFs) are heterogeneous stromal …
[HTML][HTML] Breast cancer-associated fibroblasts: where we are and where we need to go
RJ Buchsbaum, SY Oh - Cancers, 2016 - mdpi.com
Cancers are heterogeneous tissues comprised of multiple components, including tumor
cells and microenvironment cells. The tumor microenvironment has a critical role in tumor …
cells and microenvironment cells. The tumor microenvironment has a critical role in tumor …