Nucleic acid drugs—current status, issues, and expectations for exosomes
Y Yamada - Cancers, 2021 - mdpi.com
Simple Summary Nucleic acid drugs provide novel therapeutic modalities with
characteristics that differ from those of small molecules and antibodies. In this review, I focus …
characteristics that differ from those of small molecules and antibodies. In this review, I focus …
Exosomes as natural delivery carriers for programmable therapeutic nucleic acid nanoparticles (NANPs)
W Ke, KA Afonin - Advanced drug delivery reviews, 2021 - Elsevier
With recent advances in nanotechnology and therapeutic nucleic acids (TNAs), various
nucleic acid nanoparticles (NANPs) have demonstrated great promise in diagnostics and …
nucleic acid nanoparticles (NANPs) have demonstrated great promise in diagnostics and …
The advances and challenges in utilizing exosomes for delivering cancer therapeutics
M Yang, SY Wu - Frontiers in pharmacology, 2018 - frontiersin.org
Nanotechnology plays an important role in advancing treatment and diagnosis of a variety of
human diseases. The use of nanocarriers often leads to better pharmacokinetic and safety …
human diseases. The use of nanocarriers often leads to better pharmacokinetic and safety …
Exosomes and the emerging field of exosome-based gene therapy
AJ O'Loughlin, CA Woffindale… - Current gene …, 2012 - ingentaconnect.com
Exosomes are a subtype of membrane vesicle released from the endocytic compartment of
live cells. They play an important role in endogenous cell-to-cell communication. Previously …
live cells. They play an important role in endogenous cell-to-cell communication. Previously …
Exosome-like nanovectors for drug delivery in cancer
Cancer treatment still represents a formidable challenge, despite substantial advancements
in available therapies being made over the past decade. One major issue is poor …
in available therapies being made over the past decade. One major issue is poor …
Recent advances in exosome-based drug delivery for cancer therapy
Simple Summary Exosomes derived from various sources can deliver therapeutic agents
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …
Exosomes as a drug delivery tool for cancer therapy: A new era for existing drugs and oncolytic viruses
Y Kakiuchi, S Kuroda, N Kanaya… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Exosomes are cell-derived nanovesicles involved in cell-to-cell
communications. These nanovesicles are generally considered to contain important carriers …
communications. These nanovesicles are generally considered to contain important carriers …
Exosomes as drug carriers for cancer therapy
Exosomes, biological extracellular vesicles, have recently begun to find use in targeted drug
delivery in solid tumor research. Ranging from 30–120 nm in size, exosomes are secreted …
delivery in solid tumor research. Ranging from 30–120 nm in size, exosomes are secreted …
A comprehensive overview of exosomes as drug delivery vehicles—endogenous nanocarriers for targeted cancer therapy
KB Johnsen, JM Gudbergsson, MN Skov… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Exosomes denote a class of secreted nanoparticles defined by size, surface protein and
lipid composition, and the ability to carry RNA and proteins. They are important mediators of …
lipid composition, and the ability to carry RNA and proteins. They are important mediators of …
Delivery of oligonucleotide therapeutics: chemical modifications, lipid nanoparticles, and extracellular vesicles
Oligonucleotides (ONs) comprise a rapidly growing class of therapeutics. In recent years, the
list of FDA-approved ON therapies has rapidly expanded. ONs are small (15–30 bp) …
list of FDA-approved ON therapies has rapidly expanded. ONs are small (15–30 bp) …